Anti-Nitro tyrosine 抗体 [HM.11]
Anti-Nitrotyrosine antibody [HM.11]
5
(13 Reviews)
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(84 Publications)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Nitrotyrosine antibody [HM.11] (AB7048)
ab7048 at 2 μg/ml staining Nitrotyrosine in Human liver from a severely obese patient. ab7048 was incubated for 1 hour at room temperature.
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Nitrotyrosine acts as an indicator of cellular damage and protein modification due to stress conditions. When proteins have nitrotyrosine residues their function might change which can lead to cellular signaling disruption. Nitrotyrosine is not usually part of a specific complex but it affects proteins and enzymes by altering their activity and stability contributing to larger stress response mechanisms.
Pathways
Proteins modified by nitrotyrosine are involved in cellular pathways related to oxidative stress and inflammation. Particularly pathways like the nitric oxide synthase pathway and the inflammatory response pathway include nitrotyrosine-modified proteins. It is related to proteins such as nitric oxide synthase (NOS) and superoxide dismutase (SOD) important in managing oxidative balance and stress responses in cells.
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文献 (84)
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Journal of translational medicine 21:799 PubMed37946197
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eLife 12: PubMed37267120
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International journal of molecular sciences 23: PubMed36499244
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