重组Anti-Ninjurin2抗体[EPR12038] (ab172627)
![Immunoprecipitation - Anti-Ninjurin2 antibody [EPR12038] (ab172627)](https://www.abcam.cn/ps/products/172/ab172627/Images/ab172627-196016-anti-ninjurin2-antibody-epr12038-immunoprecipitation.jpg "Immunoprecipitation - Anti-Ninjurin2 antibody [EPR12038] (ab172627)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12038] to Ninjurin2
- Suitable for: WB, IP
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-Ninjurin2抗体[EPR12038]
参阅全部 Ninjurin2 一抗 -
描述
兔单克隆抗体[EPR12038] to Ninjurin2 -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details
不适用于: ICC/IF or IHC-P -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Fetal lung and Human spleen lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR12038 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab172627于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 16 kDa.
|
|
| IP |
1/10 - 1/100.
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 16 kDa. |
|
IP
1/10 - 1/100. |
应用说明
Is unsuitable for ICC/IF or IHC-P.
靶标
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功能
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. -
组织特异性
Widely expressed. In adult, higher expression in the bone marrow and peripheral blood lymphocytes, medium in the lung, lymph node, thyroid, uterus, thymus, spleen, prostate and skeletal muscle, lower in the liver, placenta, brain, heart and kidney. In embryo, higher expression in the thymus, heart and liver, lower in the spleen, lung, brain and kidney. -
序列相似性
Belongs to the ninjurin family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4815 Human
- Entrez Gene: 29862 Mouse
- Entrez Gene: 59115 Rat
- GenBank: BC057766 Human
- Omim: 607297 Human
- SwissProt: Q9NZG7 Human
- SwissProt: Q9JL89 Mouse
- SwissProt: Q9JHE8 Rat
see all -
别名
- Nerve injury induced protein 2 antibody
- Nerve injury-induced protein 2 antibody
- NINJ2 antibody
see all
图片
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Immunoprecipitation - Anti-Ninjurin2 antibody [EPR12038] (ab172627)
Western blot analysis on immunoprecipitation pellet from (1) fetal lung lysate or (2) 1XPBS (negative control) using ab172627, and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.
Lane 1 Primary: ab172627, 1/1000 dilution
Sample: Fetal lung lysateLane 2 Primary: ab172627, 1/1000 dilution
Sample: 1XPBS (negative control)
All lanes : Anti-Ninjurin2 antibody [EPR12038] (ab172627) at 1/1000 dilution
Lane 1 : Fetal lung lysate
Lane 2 : 1X PBS (negative control) -
![Western blot - Anti-Ninjurin2 antibody [EPR12038] (ab172627)](https://www.abcam.cn/ps/products/172/ab172627/Images/ab172627-196013-anti-ninjurin2-antibody-epr12038-western-blot.jpg)
Western blot - Anti-Ninjurin2 antibody [EPR12038] (ab172627)All lanes : Anti-Ninjurin2 antibody [EPR12038] (ab172627) at 1/1000 dilution
Lane 1 : Fetal lung lysate
Lane 2 : Human spleen lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 16 kDa -
![Anti-Ninjurin2 antibody [EPR12038] (ab172627)](https://www.abcam.cn/ps/products/172/ab172627/Images/ab172627-3-benefits-of-recombinant-antibodies.png)
Anti-Ninjurin2 antibody [EPR12038] (ab172627)
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab172627 被引用在 3 文献中.
- Li G et al. Ninjurin 2 overexpression promotes human colorectal cancer cell growth in vitro and in vivo. Aging (Albany NY) 11:8526-8541 (2019). PubMed: 31597121
- Zhou LN et al. Ninjurin2 overexpression promotes glioma cell growth. Aging (Albany NY) 11:11136-11147 (2019). PubMed: 31794427
- Jing D et al. Targeting ninjurin 2 by miR-764 regulates hydrogen peroxide (H2O2)-induced neuronal cell death. Biochem Biophys Res Commun 505:1180-1188 (2018). PubMed: 30318119