Anti-NFYA抗体(ab6558)
Key features and details
- Rabbit polyclonal to NFYA
- Suitable for: ELISA, IP, EMSA, WB
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-NFYA抗体
参阅全部 NFYA 一抗 -
描述
兔多克隆抗体to NFYA -
宿主
Rabbit -
经测试应用
适用于: ELISA, IP, EMSA, WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Monkey
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免疫原
Synthetic peptide corresponding to Human NFYA (N terminal) conjugated to keyhole limpet haemocyanin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.01% Sodium azide
Constituents: 0.88% Sodium chloride, 0.424% Tripotassium orthophosphate -
Concentration information loading... -
纯度
Ion Exchange Chromatography -
纯化说明
Anti-NF-Y (a) antibody was prepared from monospecific antiserum by a multi-step procedure that includes delipidation, salt fractionation and ion exchange chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA |
1/10000.
|
|
| IP |
Use at an assay dependent concentration.
|
|
| EMSA |
Use at an assay dependent concentration.
1-2 ul/assay. |
|
| WB | (1) |
1/1000.
|
| 说明 |
|---|
|
ELISA
1/10000. |
|
IP
Use at an assay dependent concentration. |
|
EMSA
Use at an assay dependent concentration. 1-2 ul/assay. |
|
WB
1/1000. |
靶标
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功能
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. -
序列相似性
Belongs to the NFYA/HAP2 subunit family. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 4800 Human
- Entrez Gene: 18044 Mouse
- Omim: 189903 Human
- SwissProt: P23511 Human
- SwissProt: P23708 Mouse
- Unigene: 10441 Human
- Unigene: 4929 Mouse
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别名
- CAAT box DNA binding protein subunit A antibody
- CAAT box DNA-binding protein subunit A antibody
- CBF A antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab6558 被引用在 7 文献中.
- Amirteimouri S et al. Epigenetic role of the nuclear factor NF-Y on ID gene family in endometrial tissues of women with endometriosis: a case control study. Reprod Biol Endocrinol 17:32 (2019). PubMed: 30876429
- Hiramoto M et al. A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression. Int J Mol Med 41:717-728 (2018). WB ; Rat . PubMed: 29207083
- Ma H et al. ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. Oncotarget 6:1049-63 (2015). IP, ChIP ; Human . PubMed: 25473899
- Lagadec C et al. The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells. Stem Cells 32:135-44 (2014). PubMed: 24022895
- Zhang Z et al. Immune mediators regulate CFTR expression through a bifunctional airway-selective enhancer. Mol Cell Biol 33:2843-53 (2013). PubMed: 23689137
- Hou Y et al. DNA Demethylation and USF Regulate the Meiosis-Specific Expression of the Mouse Miwi. PLoS Genet 8:e1002716 (2012). EMSA ; Mouse . PubMed: 22661915
- Grskovic M et al. Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet 3:e145 (2007). EMSA ; Human . PubMed: 17784790