Anti-Neuroligin 2抗体(ab177107)
Key features and details
- Rabbit polyclonal to Neuroligin 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Neuroligin 2抗体
参阅全部 Neuroligin 2 一抗 -
描述
兔多克隆抗体to Neuroligin 2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Synthetic peptide corresponding to Human Neuroligin 2 (internal sequence). NP_065846.1
Database link: Q8NFZ4 -
阳性对照
- HeLa lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in 200ul sterile H2O. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab177107于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).
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| 说明 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa). |
靶标
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相关性
Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini. -
细胞定位
Cell Membrane -
数据库链接
- Entrez Gene: 57555 Human
- Entrez Gene: 216856 Mouse
- Entrez Gene: 117096 Rat
- Omim: 606479 Human
- SwissProt: Q8NFZ4 Human
- SwissProt: Q69ZK9 Mouse
- SwissProt: Q62888 Rat
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别名
- KIAA1366 antibody
- MGC67386 antibody
- NL2 antibody
see all
图片
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Western blot - Anti-Neuroligin 2 antibody (ab177107)Anti-Neuroligin 2 antibody (ab177107) at 1/500 dilution + HeLa lysate
Predicted band size: 91 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab177107 被引用在 2 文献中.
- Wen J et al. The cAMP Response Element- Binding Protein/Brain-Derived Neurotrophic Factor Pathway in Anterior Cingulate Cortex Regulates Neuropathic Pain and Anxiodepression Like Behaviors in Rats. Front Mol Neurosci 15:831151 (2022). PubMed: 35401106
- Kanellopoulos AH et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J 37:427-445 (2018). PubMed: 29335280