Anti-Neurobeachin抗体(ab58563)
Key features and details
- Goat polyclonal to Neurobeachin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Neurobeachin抗体
参阅全部 Neurobeachin 一抗 -
描述
山羊多克隆抗体to Neurobeachin -
宿主
Goat -
特异性
This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1). -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog, Pufferfish, Zebrafish
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免疫原
Synthetic peptide:
C-DFNRWHYEHQNRY
, corresponding to C terminal amino acids 2934-2946 of Human Neurobeachin -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab58563于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 5 - 10 µg/ml.
|
| 说明 |
|---|
|
IHC-P
Use a concentration of 5 - 10 µg/ml. |
靶标
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功能
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. -
组织特异性
Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine. -
序列相似性
Belongs to the WD repeat neurobeachin family.
Contains 1 BEACH domain.
Contains 5 WD repeats. -
结构域
RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer. -
细胞定位
Cytoplasm. Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 26960 Human
- Entrez Gene: 26422 Mouse
- Entrez Gene: 310425 Rat
- Omim: 604889 Human
- SwissProt: Q8NFP9 Human
- SwissProt: Q9EPN1 Mouse
- Unigene: 491172 Human
- Unigene: 384353 Mouse
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别名
- BCL8B antibody
- FLJ10197 antibody
- KIAA1544 antibody
see all
数据表及文件
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Datasheet download
文献 (0)
ab58563 尚未被引用在任何文献中。
