重组Anti-NELL2抗体[EPR13539] (ab181376)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13539] to NELL2
- Suitable for: WB, IP
- Reacts with: Human
Related conjugates and formulations
概述
-
产品名称
Anti-NELL2抗体[EPR13539]
参阅全部 NELL2 一抗 -
描述
兔单克隆抗体[EPR13539] to NELL2 -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details
不适用于: ICC/IF or IHC-P -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human NELL2 aa 550-650. The exact sequence is proprietary.
Database link: Q99435 -
阳性对照
- Human hypothalamus tissue lysate; Human fetal brain tissue lysate
-
常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
-
纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
EPR13539 -
同种型
IgG -
研究领域
相关产品
-
Alternative Versions
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab181376于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 116 kDa (predicted molecular weight: 91 kDa).
|
|
IP |
1/10 - 1/100.
|
说明 |
---|
WB
1/1000 - 1/10000. Detects a band of approximately 116 kDa (predicted molecular weight: 91 kDa). |
IP
1/10 - 1/100. |
靶标
-
序列相似性
Contains 6 EGF-like domains.
Contains 1 TSP N-terminal (TSPN) domain.
Contains 5 VWFC domains. -
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 4753 Human
- Omim: 602320 Human
- SwissProt: Q99435 Human
- Unigene: 505326 Human
-
别名
- A330108N19Rik antibody
- Mel91 antibody
- MEL91 protein antibody
see all
图片
-
All lanes : Anti-NELL2 antibody [EPR13539] (ab181376) at 1/1000 dilution
Lane 1 : Human hypothalamus tissue lysate
Lane 2 : Human fetal brain tissue lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 91 kDa -
Western blot analysis on immunoprecipitation pellet from fetal brain lysate using ab181376 at 1/10 dilution to immunoprecipitate NELL2.
数据表及文件
-
SDS download
-
Datasheet download
Certificate of Compliance
文献 (4)
ab181376 被引用在 4 文献中.
- Suvarna K et al. Slit2 signaling stimulates Ewing sarcoma growth. Genes Cancer 13:88-99 (2022). PubMed: 36533189
- Jayabal P et al. NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth. Cell Rep 36:109254 (2021). PubMed: 34233189
- Jayabal P et al. EZH2 suppresses endogenous retroviruses and an interferon response in cancers. Genes Cancer 12:96-105 (2021). PubMed: 34966479
- Tong L et al. The tRNA-Derived Fragment-3017A Promotes Metastasis by Inhibiting NELL2 in Human Gastric Cancer. Front Oncol 10:570916 (2020). PubMed: 33665159