重组Anti-NAIP抗体[EPR6169] (ab129079)
![Western blot - Anti-NAIP antibody [EPR6169] (ab129079)](https://www.abcam.cn/ps/products/129/ab129079/Images/ab129079-483906-anti-naip-antibody-epr6169-westernblot-human.jpg "Western blot - Anti-NAIP antibody [EPR6169] (ab129079)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6169] to NAIP
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-NAIP抗体[EPR6169]
参阅全部 NAIP 一抗 -
描述
兔单克隆抗体[EPR6169] to NAIP -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- WB: Human tonsil and Human placenta tissue lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
解离常数（KD）
KD = 1.33 x 10 -11 M Learn more about KD -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR6169 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab129079于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/20000. Detects a band of approximately 160 kDa.
For unpurified use at 1/1000 - 1/10000. |
| 说明 |
|---|
|
WB
1/20000. Detects a band of approximately 160 kDa. For unpurified use at 1/1000 - 1/10000. |
靶标
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功能
Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy. -
组织特异性
Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord. -
序列相似性
Contains 3 BIR repeats.
Contains 1 NACHT domain. - Information by UniProt
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数据库链接
- Entrez Gene: 100510692 Human
- Entrez Gene: 4671 Human
- Omim: 600355 Human
- SwissProt: Q13075 Human
- Unigene: 654500 Human
- Unigene: 710305 Human
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别名
- Baculoviral IAP repeat containing 1 antibody
- Baculoviral IAP repeat-containing protein 1 antibody
- BIRC 1 antibody
see all
图片
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Western blot - Anti-NAIP antibody [EPR6169] (ab129079)All lanes : Anti-NAIP antibody [EPR6169] (ab129079) at 1/20000 dilution (Purified)
Lane 1 : Human placenta lysate
Lane 2 : Human tonsil lysate
Lysates/proteins at 15 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Observed band size: 150 kDa why is the actual band size different from the predicted?We are unsure about the nature of the extra bands.
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![Anti-NAIP antibody [EPR6169] (ab129079)](https://www.abcam.cn/ps/products/129/ab129079/Images/ab129079-3-benefits-of-recombinant-antibodies.png)
Anti-NAIP antibody [EPR6169] (ab129079)
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab129079 被引用在 1 文献中.
- Wu MS et al. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Mol Cancer Ther 12:1728-37 (2013). WB . PubMed: 23699656