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AB174278

重组Anti-MYO19抗体[EPR12551-17]

Anti-MYO19 antibody [EPR12551-17]

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(1 Publication)

Rabbit Recombinant Monoclonal MYO19 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

查看别名

MYOHD1, MYO19, Unconventional myosin-XIX, Myosin head domain-containing protein 1

1 Images
Western blot - Anti-MYO19 antibody [EPR12551-17] (AB174278)
  • WB

Supplier Data

Western blot - Anti-MYO19 antibody [EPR12551-17] (AB174278)

All lanes:

Western blot - Anti-MYO19 antibody [EPR12551-17] (ab174278) at 1/1000 dilution

Lane 1:

HeLa cell lysate at 10 µg

Lane 2:

A549 cell lysate at 10 µg

Lane 3:

K562 cell lysate at 10 µg

Lane 4:

293T cell lysate at 10 µg

Predicted band size: 109 kDa

false

不同偶联物与剂型 (1)

  • Carrier free

    Anti-MYO19 antibody [EPR12551-17] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR12551-17

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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替代产品

Primary Antibodies

AB174286

Anti-MYO19 antibody [EPR12551-13]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-MYO19 antibody [EPR12551-13] (AB174286)

  • 5
  • 1

搭配使用产品

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Anti-STK25 antibody [EPR10306]

RabMAb|Recombinant

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  • 2
  • 1
Primary Antibodies

AB188029

Anti-MIRO1 antibody [CL1083]

KO Validated

Western blot - Anti-MIRO1 antibody [CL1083] (AB188029)

  • 4
  • 4
Primary Antibodies

AB176331

Anti-CRMP5 antibody [EPR13127(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP5 antibody [EPR13127(B)] (AB176331)

  • 0
  • 0
Primary Antibodies

AB110329

Anti-Mitofilin antibody [2E4AD5] - Mitochondrial Marker

Lab Essentials

Western blot - Anti-Mitofilin antibody [2E4AD5] - Mitochondrial Marker (AB110329)

  • 5
  • 3
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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产品详情

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
存储溶液
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Conditional Ambient
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The MYO19 protein also known as Myosin XIX functions as an ATP-dependent motor protein. It possesses a molecular mass of approximately 119 kDa and is part of the myosin superfamily. This protein is known for its role in cellular processes requiring motility including vesicle and organelle transport. MYO19 is widely expressed in tissues with notable expression in the brain and skeletal muscles suggesting its importance in those regions.
Biological function summary

MYO19 contributes to mitochondrial dynamics by participating in mitochondrial motility and positioning within cells. While MYO19 is not part of a larger protein complex it interacts with the mitochondrial outer membrane and aids in tethering mitochondria to the cytoskeleton. This interaction is essential for maintaining proper cellular function specifically in energy-demanding tissues.

Pathways

MYO19 interacts with cellular transport mechanisms notably involving the actin cytoskeleton pathway. The protein facilitates mitochondrial movement along actin filaments. It shares pathways with other myosin family members such as MYO5 which are involved in intracellular transport. Additionally MYO19's role in actin-related pathways underlines its involvement in regulating cellular energy distribution and homeostasis.

MYO19 has potential links with neurodegenerative diseases and muscular disorders. Disruption in MYO19 function may lead to impaired mitochondrial distribution contributing to the pathology of conditions like amyotrophic lateral sclerosis (ALS). Additionally the protein shows possible connections with neurofilament-associated proteins suggesting a role in neural health. Such associations highlight the significance of MYO19 in understanding disease mechanisms and designing therapeutic strategies.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed : 19932026, PubMed : 23568824, PubMed : 25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed : 25447992). May be involved in mitochondrial transport or positioning (PubMed : 23568824).
See full target information MYO19
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:8051 PubMed40877279

2025

Translational repression by 4E-T is crucial to maintain the prophase-I arrest in vertebrate oocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Andreas Heim,Shiya Cheng,Jan Orth,Florian Stengel,Melina Schuh,Thomas U Mayer
View all publications
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Abcam Product Promise

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