Anti-Myeloperoxidase抗体(ab9535)
Key features and details
- Rabbit polyclonal to Myeloperoxidase
- Suitable for: ICC, IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-Myeloperoxidase抗体
参阅全部 Myeloperoxidase 一抗 -
描述
兔多克隆抗体to Myeloperoxidase -
宿主
Rabbit -
经测试应用
适用于: ICC, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
-
免疫原
Full length native protein (purified) corresponding to Human Myeloperoxidase. Myeloperoxidase isolated from human granulocytes.
Database link: P05164 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.3
Preservative: 0.05% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
骨髓瘤
unknown -
同种型
IgG -
轻链类型
unknown -
研究领域
相关产品
-
Assay kits
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
|
|
| IHC-P | (28) |
1/25 - 1/50.
|
| 说明 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
IHC-P
1/25 - 1/50. |
靶标
-
功能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
疾病相关
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
序列相似性
Belongs to the peroxidase family. XPO subfamily. -
细胞定位
Lysosome. - Information by UniProt
-
数据库链接
- Entrez Gene: 4353 Human
- Entrez Gene: 17523 Mouse
- Omim: 606989 Human
- SwissProt: P05164 Human
- SwissProt: P11247 Mouse
- Unigene: 458272 Human
- Unigene: 4668 Mouse
-
别名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
图片
-
Immunocytochemistry - Anti-Myeloperoxidase antibody (ab9535)Image courtesy of Carl Hobbs, Kings College London, U.K
Ab9535 staining of multinucleated cell (Blue) in human blood smear. Antibody was used at 1/200 for 1 hour at 21°C.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myeloperoxidase antibody (ab9535)Immunohistochemical analysis of formalin-fixed, paraffin-embedded human B cell lymphoma tissue, staining Myeloperoxidase with ab9535.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (320)
ab9535 被引用在 320 文献中.
- Ogawa K et al. Association between tissue stress reaction and ACE2/TMPRSS2 expression in endometria of reproductive aged women before and during Covid-19 pandemic. BMC Womens Health 23:229 (2023). PubMed: 37142998
- Zhang Z et al. Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage. Aging Dis 14:966-991 (2023). PubMed: 37191423
- Fleischman DA et al. Clinical and histopathological features of rostrolateral nasal alar arteriopathy of German shepherd dogs. Vet Dermatol 34:441-451 (2023). PubMed: 37221296
- Barreto-Arce LJ et al. Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator. Front Neurosci 17:1157236 (2023). PubMed: 37397458
- Lake BB et al. An atlas of healthy and injured cell states and niches in the human kidney. Nature 619:585-594 (2023). PubMed: 37468583