Anti-Myeloid Precursor Cells抗体[ER-MP58] (ab63860)
Key features and details
- Rat monoclonal [ER-MP58] to Myeloid Precursor Cells
- Suitable for: Flow Cyt, IHC-Fr, ICC/IF, IP
- Reacts with: Mouse
- Isotype: IgG2a
概述
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产品名称
Anti-Myeloid Precursor Cells抗体[ER-MP58] -
描述
大鼠单克隆抗体[ER-MP58] to Myeloid Precursor Cells -
宿主
Rat -
经测试应用
适用于: Flow Cyt, IHC-Fr, ICC/IF, IPmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Myeloid Precursor Cells. Balb/c macrophage precursor cell hybrids
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
ER-MP58 -
骨髓瘤
Y3/Ag1.2.3 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63860于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt | ||
| IHC-Fr | ||
| ICC/IF | ||
| IP |
| 说明 |
|---|
IHC-P: Use at an assay dependent dilution (PMID 19720836).
IHC-Fr: 1/25 - 1/100.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
ER-MP58 is expressed by all bone marrow derived M-CSF- and GM-CSF-responsive myeloid blood cell precursors. The expression of ER-MP58 remains at a high level throughout the precursor/monocyte stage and is down regulated upon maturation into mature macrophages. The ER-MP58 antigen is used to distinguish between early myeloid committed cells and other haematopoietic progenitors cells in the BM. -
细胞定位
Cell Membrane
实验方案
数据表及文件
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Datasheet download
文献 (2)
ab63860 被引用在 2 文献中.
- Karpurapu M et al. Functional PU.1 in macrophages has a pivotal role in NF-?B activation and neutrophilic lung inflammation during endotoxemia. Blood 118:5255-66 (2011). Flow Cyt ; Mouse . PubMed: 21937699
- Lu X & Kang Y Chemokine (C-C motif) ligand 2 engages CCR2+ stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone. J Biol Chem 284:29087-96 (2009). IHC-P ; Mouse . PubMed: 19720836
