Anti-Mycobacterium tuberculosis抗体(ab905)
Key features and details
- Rabbit polyclonal to Mycobacterium tuberculosis
- Suitable for: IHC-P
- Isotype: IgG
概述
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产品名称
Anti-Mycobacterium tuberculosis抗体
参阅全部 Mycobacterium tuberculosis 一抗 -
描述
兔多克隆抗体to Mycobacterium tuberculosis -
宿主
Rabbit -
特异性
This antibody is reactive with other Mycobacteria species including: M. avium, M. phlei, and M. parafortuitum. This antibody has been reported not to be reactive with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitides. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mycobacterium tuberculosis
不与反应: Escherichia coli, Salmonella typhimurium, Candida albicans -
免疫原
This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Sodium azide
Constituents: PBS, Carrier protein
Da Vinci Green Diluent -
Concentration information loading... -
纯度
IgG fraction -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Antibody Diluent
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (1) |
1/100 - 1/200. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. ABC method.
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| 说明 |
|---|
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IHC-P
1/100 - 1/200. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. ABC method. |
靶标
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相关性
Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method. -
别名
- M. tuberculosis antibody
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mycobacterium tuberculosis antibody (ab905)Lung tissue stained with ab905 at 1/500.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (25)
ab905 被引用在 25 文献中.
- Qiang L et al. A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination. Nat Commun 14:1430 (2023). PubMed: 36932056
- Gupta S et al. Development of a Highly Specific, Selective, and Sensitive Fluorescent Probe for Detection of Mycobacteria in Human Tissues. Adv Healthc Mater 11:e2102640 (2022). PubMed: 35038229
- Gan Y et al. Estradiol inhibits autophagy of Mycobacterium tuberculosis‑infected 16HBE cells and controls the proliferation of intracellular Mycobacterium tuberculosis. Mol Med Rep 25:N/A (2022). PubMed: 35425995
- Addo SO et al. Utility of anti-Mycobacterium tuberculosis antibody (ab905) for detection of mycobacterial antigens in formalin-fixed paraffin-embedded tissues from clinically and histologically suggestive extrapulmonary tuberculosis cases. Heliyon 8:e12370 (2022). PubMed: 36590545
- Plumlee CR et al. Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis. Cell Host Microbe 29:68-82.e5 (2021). PubMed: 33142108