AB108522

重组Anti-MYBPC3抗体[EPR3008(2)]

Anti-MYBPC3 antibody [EPR3008(2)]

RabMAb
Recombinant
了解详情

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(2 Publications)

Rabbit Recombinant Monoclonal MYBPC3 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

查看别名

Cardiac MyBP-C, MYBPC3

2 Images

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Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)

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Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (ab108522) at 1/1000 dilution

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Human heart tissue lysate at 10 µg

Predicted band size: 141 kDa

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Lab

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (AB108522)

Blocking and dilution buffer : 5% NFDM /TBST.

All lanes:

Western blot - Anti-MYBPC3 antibody [EPR3008(2)] (ab108522) at 1/5000 dilution

All lanes:

Human heart tissue lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 141 kDa

Observed band size: 141 kDa

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不同偶联物与剂型 (1)

Carrier free

Anti-MYBPC3 antibody [EPR3008(2)] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR3008(2)

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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产品详情

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Stable for 12 months at -20°C

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

See full target information MYBPC3

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Cell reports. Medicine 5:101520 PubMed38642550

2024

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction.

Applications

Unspecified application

Species

Unspecified reactive species

Caroline Kinnear,Abdelrahman Said,Guoliang Meng,Yimu Zhao,Erika Y Wang,Naimeh Rafatian,Neha Parmar,Wei Wei,Filio Billia,Craig A Simmons,Milica Radisic,James Ellis,Seema Mital

Cancer drug resistance (Alhambra, Calif.) 2:335-350 PubMed35582720

2019

Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation.

Applications

Unspecified application

Species

Unspecified reactive species

Akimasa Seno,Akifumi Mizutani,Kazuki Aizawa,Ryoma Onoue,Junko Masuda,Naotaka Ochi,Saki Taniguchi,Tatsuyuki Sota,Yuki Hiramoto,Taisuke Michiue,Neha Nair,Masaharu Seno

View all publications

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