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AB201941

Anti-MURF1抗体[7B8E1]

Anti-MURF1 antibody [7B8E1]

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(6 Publications)

Mouse Monoclonal MURF1 antibody. Suitable for Flow Cyt, IHC-P, ICC/IF and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human TRIM63 aa 250-350.

查看别名

IRF, MURF1, RNF28, SMRZ, TRIM63, E3 ubiquitin-protein ligase TRIM63, Iris RING finger protein, Muscle-specific RING finger protein 1, RING finger protein 28, RING-type E3 ubiquitin transferase TRIM63, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, MuRF-1, MuRF1

4 Images
Immunocytochemistry/ Immunofluorescence - Anti-MURF1 antibody [7B8E1] (AB201941)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-MURF1 antibody [7B8E1] (AB201941)

Immunofluorescent analysis of HeLa cells labeling MURF1 with ab201941 at 1/200 dilution. Blue : DRAQ5 fluorescent DNA dye. Red : Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Flow Cytometry - Anti-MURF1 antibody [7B8E1] (AB201941)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-MURF1 antibody [7B8E1] (AB201941)

Flow cytometric analysis of HeLa cells labeling MURF1 with ab201941 at 1/200 dilution (green) compared to a negative control (red).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURF1 antibody [7B8E1] (AB201941)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURF1 antibody [7B8E1] (AB201941)

Immunohistochemical analysis of paraffin-embedded Human muscle tissue labeling MURF1 with ab201941 at 1/200 dilution, with DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURF1 antibody [7B8E1] (AB201941)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURF1 antibody [7B8E1] (AB201941)

Immunohistochemical analysis of paraffin-embedded Human rectum cancer tissue labeling MURF1 with ab201941 at 1/200 dilution, with DAB staining.

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

7B8E1

亚型

IgG1

不含载体蛋白

No

反应种属

Human

应用

ICC/IF, IHC-P, Flow Cyt

applications

免疫原

Synthetic Peptide within Human TRIM63 aa 250-350. The exact immunogen used to generate this antibody is proprietary information.

Q969Q1

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/200 - 1/400", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/1000", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/200 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
纯化说明
Purified from tissue culture supernatant.
存储溶液
Preservative: 0.05% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
See full target information TRIM63

文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Current issues in molecular biology 47: PubMed39996807

2025

Respiratory Muscle Injury Following Acute Monocled Cobra () Envenoming: Histopathological Study in Rat Diaphragm.

Applications

Unspecified application

Species

Unspecified reactive species

Wanida Chuaikhongthong,Wipapan Khimmaktong,Natyamee Thipthong,Nissara Lorthong,Janeyuth Chaisakul

Saudi medical journal 44:355-362 PubMed37062544

2023

The histopathological effects of sleep disorders on striated muscle in rats.

Applications

Unspecified application

Species

Unspecified reactive species

İlkay Çinar,Muhammed Bozoğlan,Kürşad Aytekin,Deniz Esenyel,Cem Zeki Esenyel

Physiological reports 10:e15422 PubMed35986494

2022

Hydrogen sulfide mitigates skeletal muscle mitophagy-led tissue remodeling via epigenetic regulation of the gene writer and eraser function.

Applications

Unspecified application

Species

Unspecified reactive species

Mahavir Singh,Sathnur Pushpakumar,Yuting Zheng,Rubens P Homme,Irina Smolenkova,Sri Prakash L Mokshagundam,Suresh C Tyagi

Journal of cellular and molecular medicine 25:9724-9739 PubMed34514712

2021

Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1-AKT signalling.

Applications

Unspecified application

Species

Unspecified reactive species

Ying-Ya Cao,Zhen Wang,Tao Yu,Yuan Zhang,Zhong-Han Wang,Zi-Meng Lu,Wei-Hua Lu,Jian-Bo Yu

Journal of cellular and molecular medicine 25:1493-1506 PubMed33405354

2021

Formononetin ameliorates muscle atrophy by regulating myostatin-mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease.

Applications

Unspecified application

Species

Unspecified reactive species

Lingyu Liu,Rong Hu,Haiyan You,Jingjing Li,Yangyang Liu,Qiang Li,Xiaohui Wu,Jiawen Huang,Xiangsheng Cai,Mingqing Wang,Lianbo Wei

American journal of physiology. Endocrinology and 312:E495-E507 PubMed28246104

2017

Forkhead box O3 plays a role in skeletal muscle atrophy through expression of E3 ubiquitin ligases MuRF-1 and atrogin-1 in Cushing's syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Seol-Hee Kang,Hae-Ahm Lee,Mina Kim,Eunjo Lee,Uy Dong Sohn,Inkyeom Kim
View all publications

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