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AB121647

Anti-MURC抗体

Anti-MURC antibody

4

(2 Reviews)

|

(3 Publications)

Rabbit Polyclonal MURC antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CAVIN4 aa 50-200.

查看别名

MURC, CAVIN4, Caveolae-associated protein 4, Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-MURC antibody (AB121647)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MURC antibody (AB121647)

Immunofluorescent staining of Human cell line U-2 OS shows positivity in plasma membrane and cytoskeleton (microtubules). Recommended concentration of ab121647 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURC antibody (AB121647)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MURC antibody (AB121647)

ab121647, at 1/1000 dilution, staining MURC in paraffin-embedded Human skeletal muscle tissue, by Immunohistochemistry.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

IHC-P, ICC/IF

applications

免疫原

Recombinant Fragment Protein within Human CAVIN4 aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1-4 µg/mL", "ICCIF-species-notes": "<p>Recommend PFA Fixation and Triton X-100 treatment</p>" } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation. Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (By similarity). Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed : 18332105).
See full target information CAVIN4

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:6141 PubMed39034316

2024

Systemic delivery of full-length dystrophin in Duchenne muscular dystrophy mice.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Zhou,Chen Zhang,Weidong Xiao,Roland W Herzog,Renzhi Han

International journal of molecular sciences 22: PubMed34502507

2021

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses.

Applications

Unspecified application

Species

Unspecified reactive species

Cathrine Nordgaard,Maxim A X Tollenaere,Ana Martinez Del Val,Dorte B Bekker-Jensen,Melanie Blasius,Jesper V Olsen,Simon Bekker-Jensen

Frontiers in oncology 11:703501 PubMed34513683

2021

Integrated Bioinformatic Analysis of the Expression and Prognosis of Caveolae-Related Genes in Human Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yao Tian,Xiaofeng Liu,Jing Hu,Huan Zhang,Baichuan Wang,Yingxi Li,Li Fu,Ran Su,Yue Yu
View all publications

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