AB77995

Anti-MUC5B 抗体 [19.4E]

Name: MUC5B抗体[19.4E] (ab77995)| Abcam中文官网
Brand: Abcam Limited
SKU: AB77995
Price: 4915 CNY
Availability: InStock
Rating: 5 (2 reviews)

Anti-MUC5B antibody [19.4E]

(2 Reviews)

(30 Publications)

Anti-MUC5B antibody [19.4E] (ab77995) is a mouse monoclonal antibody detecting MUC5B in Western Blot, IHC-P, IHC-Fr, ELISA. Suitable for Human, Monkey, Mouse.

- Over 20 publications
- Trusted since 2009

查看别名

MUC5, MUC5B, Mucin-5B, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Sublingual gland mucin

1 Images

Immunohistochemistry (Frozen sections) - Anti-MUC5B antibody [19.4E] (AB77995)

IHC-Fr

Unknown

Immunohistochemistry (Frozen sections) - Anti-MUC5B antibody [19.4E] (AB77995)

ab77995 staining MUC5B in murine asthma lung tissue by Immunohistochemistry (Frozen sections). Tissue was fixed with formaldehyde, followed by incubation with the primary antibody at 4μg/ml for 16 hours at 4°C. ab77995 was coupled to biotin and Streptavidin 488 (1/250) was used to amplify the signal. Counterstained with DAPI (blue).

This image was generated using the ascites version of the product.

Image courtesy of Dr Francois Daubeuf by Abreview.

关键信息

宿主种属

Mouse

克隆

Monoclonal

克隆号

19.4E

亚型

IgG1

不含载体蛋白

反应种属

Mouse, Human, Monkey

应用

WB, IHC-P, IHC-Fr, ELISA

applications

免疫原

Synthetic Peptide within Human MUC5B. The exact immunogen used to generate this antibody is proprietary information.

Q9HC84

特异性

Does not react with human Mucin 5A or 5C.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "Deglycosylating the tissue is critical to expose epitope.", "IHCFr-species-checked": "predicted", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Mouse": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "Deglycosylating the tissue is critical to expose epitope.", "IHCFr-species-checked": "testedAndGuaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" }, "Monkey": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "Deglycosylating the tissue is critical to expose epitope.", "IHCFr-species-checked": "predicted", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" } } }

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产品详情

What is this antibody validated in?
Anti-MUC5B antibody [19.4E] (ab77995) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), ELISA in Human, Monkey, Mouse samples.

Trusted by the scientific community
Anti-MUC5B [19.4E] (ab77995) was first used in a scientific publication in 2009 and has been cited over 20 times in peer-reviewed journals.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

Preservative: 0.1% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.

See full target information MUC5B

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文献 (30)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 26: PubMed40869396

2025

Liquiritin Suppresses Intracellular and Secreted MUC5AC and MUC5B in Human Airway Epithelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ryoma Yoshio,Jun Iwashita

ImmunoTargets and therapy 13:789-803 PubMed39712952

2024

Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Jingjing Yu,Ziang Meng,Xuxu Liu,Yi Zheng,Dongbo Xue,Chenjun Hao,Liyi Wang

International journal of chronic obstructive pulmonary disease 19:1635-1647 PubMed39045541

2024

Cigarette Smoke Extract Induces MUC5AC Expression Through the ROS/ IP3R/Ca Pathway in Calu-3 Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaojuan Wu,Guoyue Zhang,Xianzhi Du

International journal of molecular medicine 53: PubMed38240085

2024

NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hong Zhou,Qun Zhang,Chenyang Liu,Jiahao Fan,Wen Huang,Nan Li,Mingxia Yang,Hong Wang,Weiping Xie,Hui Kong

Nature cardiovascular research 2:449-466 PubMed39196043

2023

Three-dimensional morphologic and molecular atlases of nasal vasculature.

Applications

Unspecified application

Species

Unspecified reactive species

Seon Pyo Hong,Myung Jin Yang,Jung Hyun Bae,Du Ri Choi,Young-Chan Kim,Myeon-Sik Yang,Byungkwan Oh,Kyung Won Kang,Sang-Myeong Lee,Bumseok Kim,Yong-Dae Kim,Ji Hoon Ahn,Gou Young Koh

Frontiers in pharmacology 13:851374 PubMed36188610

2022

Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice.

Applications

Unspecified application

Species

Unspecified reactive species

Jun Iwashita,Hikari Maeda,Momo Ishimura,Jun Murata

iScience 25:104685 PubMed35789750

2022

Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype.

Applications

Unspecified application

Species

Unspecified reactive species

Dinesh Devadoss,Arpan Acharya,Marko Manevski,Dominika Houserova,Michael D Cioffi,Kabita Pandey,Madhavan Nair,Prem Chapagain,Mehdi Mirsaeidi,Glen M Borchert,Siddappa N Byrareddy,Hitendra S Chand

Scientific reports 12:8742 PubMed35610327

2022

The normal and fibrotic mouse lung classified by spatial proteomic analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Roberta Ciccimarra,Maddalena M Bolognesi,Matteo Zoboli,Giorgio Cattoretti,Franco F Stellari,Francesca Ravanetti

Nature protocols 17:1658-1690 PubMed35546639

2022

Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection.

Applications

Unspecified application

Species

Unspecified reactive species

Rajendra Kumar Gurumurthy,Stefanie Koster,Naveen Kumar,Thomas F Meyer,Cindrilla Chumduri

Respiratory research 23:11 PubMed35042537

2022

MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model.

Applications

Unspecified application

Species

Unspecified reactive species

Xuan Huang,Weijie Guan,Bin Xiang,Wei Wang,Yanqing Xie,Jinping Zheng

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

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For licensing inquiries, please contact partnerships@abcam.com

Anti-MUC5B 抗体 [19.4E]

Anti-MUC5B antibody [19.4E]

Immunohistochemistry (Frozen sections) - Anti-MUC5B antibody [19.4E] (AB77995)

关键信息

宿主种属

克隆

克隆号

亚型

不含载体蛋白

反应种属

应用

免疫原

特异性