重组Anti-Mu Opioid Receptor抗体[UMB3] - C-terminal (ab134054)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [UMB3] to Mu Opioid Receptor - C-terminal
- Suitable for: WB
- Reacts with: Recombinant fragment
Related conjugates and formulations
概述
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产品名称
Anti-Mu Opioid Receptor抗体[UMB3] - C-terminal
参阅全部 Mu Opioid Receptor 一抗 -
描述
兔单克隆抗体[UMB3] to Mu Opioid Receptor - C-terminal -
宿主
Rabbit -
特异性
The antibody detects the band of interest in transfected cell lines. When tested in our lab, we were not able to detect any signal from the endogenous protein.
This antibody can be used in IHC and ICC/IF as demonstrated in several publications, however, it did not pass our internal validation in these applications. Please refer to PMID 20851148, 21957251, 26290245, and other references.
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经测试应用
适用于: WBmore details
不适用于: Flow Cyt -
种属反应性
与反应: Recombinant fragment
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- WB: Mu Opioid Receptor transfected HEK-293 lysate.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
UMB3 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab134054于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Detects a band of approximately 75-78 kDa (predicted molecular weight: 45 kDa).
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说明 |
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WB
1/1000 - 1/10000. Detects a band of approximately 75-78 kDa (predicted molecular weight: 45 kDa). |
靶标
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功能
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 18390 Mouse
- Entrez Gene: 25601 Rat
- SwissProt: P42866 Mouse
- SwissProt: P33535 Rat
- Unigene: 457998 Mouse
- Unigene: 10118 Rat
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别名
- hMOP antibody
- LMOR antibody
- M-OR-1 antibody
see all
图片
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All lanes : Anti-Mu Opioid Receptor antibody [UMB3] - C-terminal (ab134054) at 1/1000 dilution
Lane 1 : Mu Opioid Receptor transfected HEK-293 (Human epithelial cell line from embryonic kidney) lysate
Lane 2 : HEK-293T cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 45 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (41)
ab134054 被引用在 41 文献中.
- Wang X et al. μ-opioid receptor agonist facilitates circulating tumor cell formation in bladder cancer via the MOR/AKT/Slug pathway: a comprehensive study including randomized controlled trial. Cancer Commun (Lond) 43:365-386 (2023). PubMed: 36739595
- Fritzwanker S et al. In situ visualization of opioid and cannabinoid drug effects using phosphosite-specific GPCR antibodies. Commun Biol 6:419 (2023). PubMed: 37061609
- Yuan W et al. Lactobacillus rhamnosus GG and butyrate supplementation in rats with bone cancer reduces mechanical allodynia and increases expression of μ-opioid receptor in the spinal cord. Front Mol Neurosci 16:1207911 (2023). PubMed: 37389091
- Salimando GJ et al. Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types. Nat Commun 14:5632 (2023). PubMed: 37704594
- Mengaziol J et al. A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells. PLoS One 17:e0270317 (2022). PubMed: 36534642