Anti-MTTP/MTP抗体(ab75316)
Key features and details
- Rabbit polyclonal to MTTP/MTP
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-MTTP/MTP抗体
参阅全部 MTTP/MTP 一抗 -
描述
兔多克隆抗体to MTTP/MTP -
宿主
Rabbit -
特异性
Reactivity with human samples appears to be lot-dependent. A user reported strong western blot reactivity with a mouse cell lysate but none with a human HepG2 lysate. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab75316于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/200 - 1/2000. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa).
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| 说明 |
|---|
|
WB
1/200 - 1/2000. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa). |
靶标
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功能
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. -
组织特异性
Liver and small intestine. Also found in ovary, testis and kidney. -
疾病相关
Abetalipoproteinemia -
序列相似性
Contains 1 vitellogenin domain. -
细胞定位
Endoplasmic reticulum. - Information by UniProt
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数据库链接
- Entrez Gene: 17777 Mouse
- SwissProt: O08601 Mouse
- Unigene: 2941 Mouse
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别名
- ABL antibody
- Microsomal triglyceride transfer protein (large polypeptide 88kDa) antibody
- Microsomal triglyceride transfer protein 88kD antibody
see all
图片
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Western blot - Anti-MTTP/MTP antibody (ab75316)Anti-MTTP/MTP antibody (ab75316) at 1/500 dilution + Liver (Mouse) Tissue Lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 99 kDa
Observed band size: 99 kDa
Additional bands at: 40 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 1 minute
数据表及文件
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Datasheet download
文献 (13)
ab75316 被引用在 13 文献中.
- Yu K et al. In vivo functional characterization of EGFR variants identifies novel drivers of glioblastoma. Neuro Oncol 25:471-481 (2023). PubMed: 36044040
- Liu P et al. The DEAD-box helicase DDX3x ameliorates non-alcoholic fatty liver disease via mTORC1 signalling pathway. Liver Int 42:1793-1802 (2022). PubMed: 35460172
- Bhat N et al. Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice. J Clin Invest 132:N/A (2022). PubMed: 34855620
- Zhou C et al. Gadofullerene inhibits the degradation of apolipoprotein B100 and boosts triglyceride transport for reversing hepatic steatosis. Sci Adv 6:N/A (2020). PubMed: 32917715
- Gallego P et al. The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging. Cells 9:N/A (2020). PubMed: 32977490
