Anti-mtTFA抗体- Mitochondrial Marker (ab131607)
Key features and details
- Rabbit polyclonal to mtTFA - Mitochondrial Marker
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-mtTFA抗体- Mitochondrial Marker
参阅全部 mtTFA 一抗 -
描述
兔多克隆抗体to mtTFA - Mitochondrial Marker -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Recombinant full length protein (6x HIS-tag) corresponding to Mouse mtTFA. Native recombinant mouse mtTFA protein with a C-terminal 6-His tag.
-
阳性对照
- Rat kidney lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Concentration information loading...
-
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab131607于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (5) |
1/2000. Predicted molecular weight: 28 kDa.
|
说明 |
---|
WB
1/2000. Predicted molecular weight: 28 kDa. |
靶标
-
功能
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M. -
序列相似性
Contains 2 HMG box DNA-binding domains. -
细胞定位
Mitochondrion. - Information by UniProt
-
数据库链接
- Entrez Gene: 83474 Rat
- SwissProt: Q91ZW1 Rat
- Unigene: 18266 Rat
-
别名
- anscription factor 6-like 1 antibody
- Mitochondrial transcription factor 1 antibody
- mitochondrial transcription factor A antibody
see all
图片
-
All lanes : Anti-mtTFA antibody - Mitochondrial Marker (ab131607) at 1/2000 dilution
Lane 1 : Mouse liver whole tissue lysate
Lane 2 : Mouse hepatocytes whole cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : HRP-conjugated goat anti-rabbit IgG at 1/20000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 28 kDa
Exposure time: 10 seconds
-
Anti-mtTFA antibody - Mitochondrial Marker (ab131607) at 1/2000 dilution + Rat kidney lysate
Predicted band size: 28 kDa
数据表及文件
-
Datasheet download
文献 (158)
ab131607 被引用在 158 文献中.
- Ren L et al. Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis. Diabetologia 67:137-155 (2024). PubMed: 37843554
- Hansen FM et al. Mitochondrial phosphoproteomes are functionally specialized across tissues. Life Sci Alliance 7:N/A (2024). PubMed: 37984987
- Pileggi CA et al. The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics. Curr Res Neurobiol 5:100112 (2023). PubMed: 38020812
- Shang Q et al. Lactate Mediates High-Intensity Interval Training-Induced Promotion of Hippocampal Mitochondrial Function through the GPR81-ERK1/2 Pathway. Antioxidants (Basel) 12:N/A (2023). PubMed: 38136207
- Wada E et al. Emerin deficiency does not exacerbate cardiomyopathy in a murine model of Emery-Dreifuss muscular dystrophy caused by an LMNA gene mutation. J Physiol Sci 73:27 (2023). PubMed: 37940872