Anti-MTMR6抗体(ab69875)
Key features and details
- Mouse polyclonal to MTMR6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MTMR6抗体
参阅全部 MTMR6 一抗 -
描述
小鼠多克隆抗体to MTMR6 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human MTMR6. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- MTMR6 transfected 293T cell lysate and human kidney tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab69875于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa). |
靶标
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功能
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. -
组织特异性
Expressed in CD4+ T-cells. -
序列相似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 myotubularin phosphatase domain. -
细胞定位
Nucleus envelope. - Information by UniProt
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数据库链接
- Entrez Gene: 9107 Human
- Omim: 603561 Human
- SwissProt: Q9Y217 Human
- Unigene: 643702 Human
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别名
- 4022440C11Rik antibody
- AI428804 antibody
- AU041072 antibody
see all
图片
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Western blot - Anti-MTMR6 antibody (ab69875)Anti-MTMR6 antibody (ab69875) at 1/500 dilution + human kidney tissue lysate at 50 µg
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa -
Western blot - Anti-MTMR6 antibody (ab69875)All lanes : Anti-MTMR6 antibody (ab69875) at 1/500 dilution
Lane 1 : MTMR6 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 72 kDa
Observed band size: 72 kDa
数据表及文件
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Datasheet download
文献 (1)
ab69875 被引用在 1 文献中.
- Campa CC et al. Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes. Nat Chem Biol N/A:N/A (2018). PubMed: 29915378
