重组Anti-MTAP抗体[EPR6892] (ab126623)
![Western blot - Anti-MTAP antibody [EPR6892] (ab126623)](https://www.abcam.cn/ps/products/126/ab126623/Images/ab126623-458230-anti-mtap-antibody-epr6892-westernblot-human-mouse-rat.jpg "Western blot - Anti-MTAP antibody [EPR6892] (ab126623)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6892] to MTAP
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
概述
-
产品名称
Anti-MTAP抗体[EPR6892]
参阅全部 MTAP 一抗 -
描述
兔单克隆抗体[EPR6892] to MTAP -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF or IHC-P -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
阳性对照
- WB: HeLa whole cell lysate, human heart lysate, NIH/3T3 whole cell lysate, mouse heart lysate, rat c6 whole cell lysate, rat heart lysate
-
常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR6892 -
同种型
IgG -
研究领域
相关产品
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab126623于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa).
|
| 说明 |
|---|
|
WB
1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 31 kDa). |
应用说明
Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
靶标
-
功能
Plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. -
组织特异性
Ubiquitously expressed. -
序列相似性
Belongs to the PNP/MTAP phosphorylase family. -
细胞定位
Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 4507 Human
- Entrez Gene: 66902 Mouse
- Entrez Gene: 298227 Rat
- Omim: 156540 Human
- SwissProt: Q13126 Human
- SwissProt: Q9CQ65 Mouse
- Unigene: 193268 Human
- Unigene: 28500 Mouse
-
别名
- 5' methylthioadenosine phosphorylase antibody
- 5''-methylthioadenosine phosphorylase antibody
- BDMF antibody
see all
图片
-
Western blot - Anti-MTAP antibody [EPR6892] (ab126623)Lanes 1 & 3 : Anti-MTAP antibody [EPR6892] (ab126623) at 1/1000 dilution (Purified)
Lanes 2 & 4-6 : Anti-MTAP antibody [EPR6892] (ab126623) at 1/1000 dilution
Lane 1 : HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysate
Lane 2 : Human heart lysate
Lane 3 : NIH/3T3 (Mouse embryonic fibroblast) whole cell lysate
Lane 4 : Mouse heart lysate
Lane 5 : C6 (Rat glial tumor glial cell) whole cell lysate
Lane 6 : Rat heart lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Predicted band size: 31 kDa -
![Anti-MTAP antibody [EPR6892] (ab126623)](https://www.abcam.cn/ps/products/126/ab126623/Images/ab126623-2-benefits-of-recombinant-antibodies.png)
Anti-MTAP antibody [EPR6892] (ab126623)
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab126623 被引用在 2 文献中.
- Pauli C et al. A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients. Mol Cancer Res 20:244-252 (2022). PubMed: 34728552
- Barekatain Y et al. Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine. Nat Commun 12:4228 (2021). PubMed: 34244484