Anti-MRP3抗体(ab226804)
Key features and details
- Rabbit polyclonal to MRP3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-MRP3抗体
参阅全部 MRP3 一抗 -
描述
兔多克隆抗体to MRP3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment within Human MRP3 (internal sequence). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: O15438-1 -
阳性对照
- WB: HCT 116 membrane extract.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab226804于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 169 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 169 kDa. |
靶标
-
功能
May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. -
组织特异性
Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney. -
序列相似性
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
细胞定位
Membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 8714 Human
- Omim: 604323 Human
- SwissProt: O15438 Human
- Unigene: 463421 Human
-
别名
- ABC 31 antibody
- ABC31 antibody
- ABCC 3 antibody
see all
图片
-
Western blot - Anti-MRP3 antibody (ab226804)All lanes : Anti-MRP3 antibody (ab226804) at 1/500 dilution
Lane 1 : HCT 116 (Human colorectal carcinoma cell line) whole cell extract
Lane 2 : HCT 116 (Human colorectal carcinoma cell line) membrane extract
Lysates/proteins at 30 µg per lane.
Predicted band size: 169 kDa5% SDS-PAGE gel.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab226804 被引用在 1 文献中.
- Lu Y et al. HNF1A inhibition induces the resistance of pancreatic cancer cells to gemcitabine by targeting ABCB1. EBioMedicine 44:403-418 (2019). PubMed: 31103629