Anti-MRG15抗体(ab106818)
Key features and details
- Goat polyclonal to MRG15
- Suitable for: WB
- Reacts with: Mouse, Rat, Human, Pig
- Isotype: IgG
概述
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产品名称
Anti-MRG15抗体
参阅全部 MRG15 一抗 -
描述
山羊多克隆抗体to MRG15 -
宿主
Goat -
特异性
This antibody is expected to recognise both reported isoforms. -
经测试应用
适用于: WBmore details
不适用于: IHC-P -
种属反应性
与反应: Mouse, Rat, Human, Pig
预测可用于: Cow -
免疫原
Synthetic peptide:
APKQDPKPKFQEG-C
, corresponding to N terminal amino acids 2-14 of Human MRG15 (NP_006782.1; NP_996670.1.) -
常规说明
This product will identify isoform 1 and isoform 2.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106818于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa.
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa. 1 hour primary incubation is recommended for this product. |
靶标
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功能
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci. -
序列相似性
Belongs to the MRG family. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 614390 Cow
- Entrez Gene: 10933 Human
- Entrez Gene: 21761 Mouse
- Entrez Gene: 627352 Mouse
- Entrez Gene: 100154823 Pig
- Entrez Gene: 300891 Rat
- Omim: 607303 Human
- SwissProt: Q9UBU8 Human
see all -
别名
- CG6363 antibody
- Eaf3 antibody
- Esa1p associated factor 3 homolog antibody
see all
图片
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All lanes : Anti-MRG15 antibody (ab106818) at 0.3 µg/ml
Lane 1 : Mouse liver tissue lysate (in RIPA buffer)
Lane 2 : Rat liver tissue lysate (in RIPA buffer)
Lane 3 : Pig liver tissue lysate (in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 41 kDa
Additional bands at: 37 kDa. We are unsure as to the identity of these extra bands.Goat Anti-MRG15 / MORF4L1 Antibody (EB06079) - Everest Biotech Ltd
Primary incubation was 1 hour. Detected by chemiluminescence. -
All lanes :
Lane 1 : NIH3T3 cell lysate (in RIPA buffer)
Lane 2 : HepG2 cell lysate (in RIPA buffer)
Lysates/proteins at 35 µg per lane.
Predicted band size: 41 kDa
Additional bands at: 37 kDa. We are unsure as to the identity of these extra bands.Primary incubation was 1 hour. Detected by chemiluminescence.
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Anti-MRG15 antibody (ab106818) at 0.1 µg/ml + Mouse Liver Lysate in RIPA buffer at 35 µg
Predicted band size: 41 kDa
Primary incubation 1 hour.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab106818 尚未被引用在任何文献中。