Anti-MOSC2抗体(ab224097)
Key features and details
- Rabbit polyclonal to MOSC2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MOSC2抗体
参阅全部 MOSC2 一抗 -
描述
兔多克隆抗体to MOSC2 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Cynomolgus monkey
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免疫原
Recombinant fragment corresponding to Human MOSC2 aa 200-300.
Database link: Q969Z3 -
阳性对照
- WB: Human cell line TD47D IHC-P: Human liver tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab224097于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 29,38 kDa.
|
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| IHC-P |
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
WB
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 29,38 kDa. |
|
IHC-P
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex. -
序列相似性
Contains 1 MOSC domain. -
细胞定位
Mitochondrion outer membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 102136254 Cynomolgus monkey
- Entrez Gene: 54996 Human
- Omim: 614127 Human
- SwissProt: Q9GKW0 Cynomolgus monkey
- SwissProt: Q969Z3 Human
- Unigene: 369042 Human
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别名
- FLJ20605 antibody
- MARC2 antibody
- Mitochondrial amidoxime reducing component 2 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MOSC2 antibody (ab224097)
Paraffin-embedded human liver tissue stained for MOSC2 using ab224097 at 1/500 in immunohistochemical analysis.
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Western blot - Anti-MOSC2 antibody (ab224097)Anti-MOSC2 antibody (ab224097) at 0.4 µg/ml + Human cell line TD47D
Predicted band size: 29,38 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab224097 被引用在 2 文献中.
- Wu D et al. Downregulation of MARC2 Promotes Immune Escape and Is Associated With Immunosuppression of Hepatocellular Carcinoma. Front Genet 12:790093 (2021). PubMed: 35173763
- Wu D et al. A novel mitochondrial amidoxime reducing component 2 is a favorable indicator of cancer and suppresses the progression of hepatocellular carcinoma by regulating the expression of p27. Oncogene 39:6099-6112 (2020). PubMed: 32811980