Anti-Monoacylglycerol Lipase/MGL抗体(ab24701)
Key features and details
- Rabbit polyclonal to Monoacylglycerol Lipase/MGL
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Cow, Human, Monkey, African green monkey
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Monoacylglycerol Lipase/MGL抗体
参阅全部 Monoacylglycerol Lipase/MGL 一抗 -
描述
兔多克隆抗体to Monoacylglycerol Lipase/MGL -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Rat, Cow, Human, Monkey, African green monkey -
免疫原
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, PBS -
Concentration information loading... -
纯度
IgG fraction -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24701于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (3) |
Use at an assay dependent concentration.
|
| WB | (6) |
1/200. Predicted molecular weight: 33 kDa.
|
| 说明 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
|
WB
1/200. Predicted molecular weight: 33 kDa. |
靶标
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功能
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. -
组织特异性
Detected in adipose tissue, lung, liver, kidney, brain and heart. -
通路
Glycerolipid metabolism; triacylglycerol degradation. -
序列相似性
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family. - Information by UniProt
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数据库链接
- Entrez Gene: 505290 Cow
- Entrez Gene: 11343 Human
- Entrez Gene: 23945 Mouse
- Entrez Gene: 29254 Rat
- Omim: 609699 Human
- SwissProt: Q99685 Human
- SwissProt: O35678 Mouse
- SwissProt: Q8R431 Rat
see all -
别名
- EC 3.1.1.23 antibody
- HU K5 antibody
- HU-K5 antibody
see all
图片
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Western blot - Anti-Monoacylglycerol Lipase/MGL antibody (ab24701)Anti-Monoacylglycerol Lipase/MGL antibody (ab24701) at 1/200 dilution + Rat brown fat at 20 µg
Predicted band size: 33 kDa
Rat brown fat, 20 ug Dilution: 1/200
数据表及文件
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SDS download
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Datasheet download
文献 (39)
ab24701 被引用在 39 文献中.
- Yadav-Samudrala BJ et al. Effects of acute Δ9-tetrahydrocannabinol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice. Brain Res 1822:148638 (2024). PubMed: 37858856
- Scipioni L et al. Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance. Int J Mol Sci 24:N/A (2023). PubMed: 37047663
- Xu C et al. Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms. Cells 11:N/A (2022). PubMed: 35269478
- Kra G et al. Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows. Animals (Basel) 12:N/A (2022). PubMed: 35327191
- Mitra S et al. A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence. Addict Biol 26:e13007 (2021). PubMed: 33496035