Anti-MMP25抗体[MM0029-2B5] (ab56309)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP25 antibody [MM0029-2B5] (ab56309)](https://www.abcam.cn/ps/products/56/ab56309/Images/MMP25-Primary-antibodies-ab56309-1.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP25 antibody [MM0029-2B5] (ab56309)")
Key features and details
- Mouse monoclonal [MM0029-2B5] to MMP25
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-MMP25抗体[MM0029-2B5] -
描述
小鼠单克隆抗体[MM0029-2B5] to MMP25 -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Purified Human recombinant MMP25
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 0.5ml sterile PBS. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MM0029-2B5 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab56309于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/500.
|
| 说明 |
|---|
|
IHC-P
1/50 - 1/500. |
靶标
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功能
May activate progelatinase A. -
组织特异性
Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. -
序列相似性
Belongs to the peptidase M10A family.
Contains 4 hemopexin repeats. -
结构域
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. -
翻译后修饰
The precursor is cleaved by a furin endopeptidase. -
细胞定位
Cell membrane. Secreted, extracellular space, extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 64386 Human
- Omim: 608482 Human
- SwissProt: Q9NPA2 Human
- Unigene: 654979 Human
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别名
- Leukolysin antibody
- matrix metallopeptidase 25 antibody
- matrix metallopeptidase like 1 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP25 antibody [MM0029-2B5] (ab56309)
ab56309 at 1/500 dilution, staining MMP25 in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).
数据表及文件
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Datasheet download
文献 (2)
ab56309 被引用在 2 文献中.
- Premadasa LS et al. Cannabinoid enhancement of lncRNA MMP25-AS1/MMP25 interaction reduces neutrophil infiltration and intestinal epithelial injury in HIV/SIV infection. JCI Insight 8:N/A (2023). PubMed: 37036007
- Yao J et al. lnc‑MICAL2‑1 sponges miR‑25 to regulate DKK3 expression and inhibits activation of the Wnt/β‑catenin signaling pathway in breast cancer. Int J Mol Med 49:N/A (2022). PubMed: 34970696
