Anti-MKRN3抗体(ab177203)
Key features and details
- Rabbit polyclonal to MKRN3
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MKRN3抗体 -
描述
兔多克隆抗体to MKRN3 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human MKRN3 aa 278-443.
Sequence:DAAQREEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDR RFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFW VEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEYPEGWG DEPPGPGGGSFSAYWH
Database link: BC044639 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in 200ul sterile H2O. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 48% PBS, 1% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab177203于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100 - 1/500.
|
|
| WB |
1/200 - 1/1000. Predicted molecular weight: 56 kDa.
|
| 说明 |
|---|
|
IHC-P
1/100 - 1/500. |
|
WB
1/200 - 1/1000. Predicted molecular weight: 56 kDa. |
靶标
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功能
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. -
组织特异性
Ubiquitous. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Contains 3 C3H1-type zinc fingers.
Contains 1 RING-type zinc finger. - Information by UniProt
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数据库链接
- Entrez Gene: 7681 Human
- Omim: 603856 Human
- SwissProt: Q13064 Human
- Unigene: 679587 Human
- Unigene: 72964 Human
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别名
- D15S9 antibody
- Makorin ring finger protein 3 antibody
- Mkrn3 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MKRN3 antibody (ab177203)
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human fetal colon tissue labeling MKRN3 with ab177203 at 1/100 dilution.
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Western blot - Anti-MKRN3 antibody (ab177203)Anti-MKRN3 antibody (ab177203) at 1/1000 dilution + A431 cell lysate
Predicted band size: 56 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab177203 被引用在 2 文献中.
- Li K et al. E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer. J Exp Med 218:N/A (2021). PubMed: 34143182
- Fanis P et al. Central Precocious Puberty Caused by Novel Mutations in the Promoter and 5'-UTR Region of the Imprinted MKRN3 Gene. Front Endocrinol (Lausanne) 10:677 (2019). PubMed: 31636607