Anti-MD1抗体(ab45424)
Key features and details
- Rabbit polyclonal to MD1
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MD1抗体
参阅全部 MD1 一抗 -
描述
兔多克隆抗体to MD1 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic 15 amino acid peptide from near the center of human MD1
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阳性对照
- Daudi cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
This antibody is an immunoaffinity purified IgG -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab45424于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 2.5 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 18 kDa).
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说明 |
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IHC-P
Use a concentration of 2.5 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 18 kDa). |
靶标
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功能
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. -
组织特异性
Highly expressed in B-cells, monocytes and tonsil. -
细胞定位
Secreted > extracellular space. Associated with CD180 at the cell surface. - Information by UniProt
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数据库链接
- Entrez Gene: 9450 Human
- Omim: 605241 Human
- SwissProt: O95711 Human
- Unigene: 653138 Human
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别名
- BPAD antibody
- dJ80N2.1 antibody
- Ly 86 antibody
see all
图片
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Anti-MD1 antibody (ab45424) at 2 µg/ml + Daudi cell lysate at 15 µg
Predicted band size: 18 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted? -
ab45424 at 2.5µg/ml staining MD1 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab45424 被引用在 2 文献中.
- Song Z et al. Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model. Front Genet 11:565479 (2020). PubMed: 33250918
- Yang HJ et al. Knockout of MD1 contributes to sympathetic hyperactivity and exacerbates ventricular arrhythmias following heart failure with preserved ejection fraction via NLRP3 inflammasome activation. Exp Physiol 105:966-978 (2020). PubMed: 32240565