AB200685

Anti-MAS1L抗体

Name: MAS1L抗体 (ab200685)| Abcam中文官网
Brand: Abcam Limited
SKU: AB200685
Price: 4560 CNY
Availability: InStock
Rating: 4 (1 reviews)

Anti-MAS1L antibody

(1 Review)

(6 Publications)

Rabbit Polyclonal MAS1L antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human MAS1L aa 1-100.

查看别名

MRG, MAS1L, Mas-related G-protein coupled receptor MRG, MAS-R, MAS1-like

1 Images

Supplier Data

Western blot - Anti-MAS1L antibody (AB200685)

All lanes:

Western blot - Anti-MAS1L antibody (ab200685)

Lane 1:

HEK293T whole cell lysate

Lane 2:

NIH3T3 whole cell lysate

Lane 3:

PC12 whole cell lysate

Predicted band size: 42 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Mouse, Rat, Human

应用

applications

免疫原

Synthetic Peptide within Human MAS1L aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

P35410

style

left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" } } }

style

left-column

style

left-column

性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

Purity is > 95% (by SDS-PAGE).

存储溶液

pH: 7.2 Preservative: 0.097% Sodium azide Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

style

left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

MAS1L sometimes referred to as MAS1-like is a protein encoded by the MAS1L gene. Its mass is approximately 37 kDa. This protein is expressed in various tissues including the central nervous system and certain peripheral tissues. MAS1L is an integral membrane protein and it localizes on the cell surface which indicates its potential involvement in signaling processes. As a G protein-coupled receptor it plays a role in transmitting signals across the cell membrane.

Biological function summary

MAS1L functions within the context of signal transduction. It engages in biological processes by potentially forming complexes with other proteins or molecules that facilitate signaling activities. This protein's ability to interact with G proteins suggests its involvement in activating downstream cellular responses influencing various cellular functions such as growth differentiation or communication between cells. The MAS1L's role in signaling implicates it in maintaining normal cellular activity and responding to environmental cues.

Pathways

MAS1L engages in signaling cascades potentially linked to the renin-angiotensin system and other related pathways that influence cardiovascular functions. In the renin-angiotensin system similar receptors like the MAS1 receptor participate suggesting that MAS1L could share functional similarities. The renin-angiotensin pathway plays an important role in regulating blood pressure and fluid balance and any interaction involving MAS1L might contribute to these physiological processes.

Abnormal expression or mutation of MAS1L could relate to cardiovascular diseases and neurological disorders. Dysfunctional signaling through MAS1L might contribute to the pathology of hypertension a condition in which the MAS1 receptor also plays a significant role highlighting potential overlap in their functional pathways. Furthermore disruptions in MAS1L activity might affect neurological functions linking it to conditions that compromise nervous system integrity.

style

left-column

style

left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

靶点信息

See full target information MAS1L

style

left-column

文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Thyroid research 17:22 PubMed39491028

2024

Losartan is more effective than angiotensin (1-7) in preventing thyroxine-induced renal injury in the rat.

Applications

Unspecified application

Species

Unspecified reactive species

Slava Malatiali,Mabayoje Oriowo

Pharmaceutical biology 60:979-989 PubMed35588103

2022

Fraxinol attenuates LPS-induced acute lung injury by equilibrating ACE-Ang II-AT1R and ACE2-Ang (1-7)-Mas and inhibiting NLRP3.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wu,Xin Yang,Yuanyuan Ju,Fei Zhao

Cells 11: PubMed35563848

2022

Cross-Talk between CB, AT, AT and Mas Receptors Responsible for Blood Pressure Control in the Paraventricular Nucleus of Hypothalamus in Conscious Spontaneously Hypertensive Rats and Their Normotensive Controls.

Applications

Unspecified application

Species

Unspecified reactive species

Krzysztof Mińczuk,Eberhard Schlicker,Barbara Malinowska

JCI insight 7: PubMed34874920

2022

Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis.

Applications

Unspecified application

Species

Unspecified reactive species

Isabella Zaidan,Luciana P Tavares,Michelle A Sugimoto,Kátia M Lima,Graziele L Negreiros-Lima,Lívia Cr Teixeira,Thais C Miranda,Bruno Vs Valiate,Allysson Cramer,Juliana Priscila Vago,Gabriel H Campolina-Silva,Jéssica Am Souza,Laís C Grossi,Vanessa Pinho,Maria Jose Campagnole-Santos,Robson As Santos,Mauro M Teixeira,Izabela Galvão,Lirlândia P Sousa

The Journal of international medical research 48:300060520943453 PubMed32790534

2020

Protective effects of irbesartan and benazepril against vaginal vascular remodeling and fibrosis in female spontaneously hypertensive rats.

Applications

Unspecified application

Species

Unspecified reactive species

Ruixin Ma,Yang Zhao,Xiaorong Yu,Ningyin Li,Qiongying Wang,Wei Liang,Xu Zhao,Jing Yu

Molecular medicine reports 16:8485-8492 PubMed28944898

2017

Effects of IQP, VEP and Spirulina platensis hydrolysates on the local kidney renin angiotensin system in spontaneously hypertensive rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jiahui Zheng,Jingyue Wang,Huanglei Pan,Hongli Wu,Difeng Ren,Jun Lu

View all publications

style

left-column

style

left-column

style

right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-MAS1L抗体

Anti-MAS1L antibody

Western blot - Anti-MAS1L antibody (AB200685)