Anti-Mare抗体(ab121346)
Key features and details
- Rabbit polyclonal to Mare
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Mare抗体
参阅全部 Mare 一抗 -
描述
兔多克隆抗体to Mare -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
-
免疫原
Recombinant fragment corresponding to Human Mare aa 60-199.
Database link: Q12980 -
阳性对照
- IHC-P: Human endometrium and prostate tissue. ICC: A431 cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121346于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
|
| IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
|
IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
组织特异性
Widely expressed. -
序列相似性
Belongs to the NPR3 family. - Information by UniProt
-
数据库链接
- Entrez Gene: 8131 Human
- Entrez Gene: 17168 Mouse
- Entrez Gene: 360505 Rat
- Omim: 600928 Human
- SwissProt: Q12980 Human
- SwissProt: Q8VIJ8 Mouse
- Unigene: 19699 Human
-
别名
- -14 gene protein antibody
- Alpha-globin regulatory element-containing gene protein antibody
- C16ORF35 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mare antibody (ab121346)
Paraffin-embedded human endometrium tissue staining MARE with ab121346 at 1/50 dilution in immunohistochemical analysis.
-
Immunocytochemistry/ Immunofluorescence - Anti-Mare antibody (ab121346)Immunofluorescent staining of Human cell line A-431 shows positivity in cytoplasm. Recommended concentration of ab121346 1-4 µg/ml. Cells treated with PFA/Triton X-100. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mare antibody (ab121346)Paraffin-embedded human prostate tissue staining MARE with ab121346 at 1/50 dilution in immunohistochemical analysis.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (5)
ab121346 被引用在 5 文献中.
- Hui JB et al. NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis. eNeuro 9:N/A (2022). PubMed: 35165201
- Wang YC et al. NPRL2 down-regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression. Hepatol Commun 6:3563-3577 (2022). PubMed: 36321403
- Li Y et al. A Novel Loss-of-Function Mutation in the NPRL3 Gene Identified in Chinese Familial Focal Epilepsy with Variable Foci. Front Genet 12:766354 (2021). PubMed: 34868250
- Bertuzzi M et al. A human minisatellite hosts an alternative transcription start site for NPRL3 driving its expression in a repeat number-dependent manner. Hum Mutat 41:807-824 (2020). PubMed: 31898848
- Yuskaitis CJ et al. Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice. Hum Mol Genet 28:2952-2964 (2019). PubMed: 31174205