Anti-MAP2抗体[MT-08] (ab118898)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP2 antibody [MT-08] (ab118898)](https://www.abcam.cn/ps/products/118/ab118898/Images/ab118898-131476-anti-map2-antibody-mt-08-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP2 antibody [MT-08] (ab118898)")
Key features and details
- Mouse monoclonal [MT-08] to MAP2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
-
产品名称
Anti-MAP2抗体[MT-08]
参阅全部 MAP2 一抗 -
描述
小鼠单克隆抗体[MT-08] to MAP2 -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Pig
-
免疫原
Full length native protein (purified) corresponding to Cow MAP2 aa 1375-1395.
-
阳性对照
- Human Cortex tissue
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
单克隆 -
克隆编号
MT-08 -
同种型
IgG1 -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab118898于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
功能
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. -
序列相似性
Contains 3 Tau/MAP repeats. -
翻译后修饰
Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. -
细胞定位
Cytoplasm, cytoskeleton. - Information by UniProt
-
数据库链接
- Entrez Gene: 4133 Human
- Entrez Gene: 17756 Mouse
- Omim: 157130 Human
- SwissProt: P11137 Human
- SwissProt: P20357 Mouse
- Unigene: 368281 Human
- Unigene: 256966 Mouse
- Unigene: 436793 Mouse
-
别名
- DKFZp686I2148 antibody
- MAP 2 antibody
- MAP dendrite specific antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP2 antibody [MT-08] (ab118898)ab118898 at 10ug/ml staining MAP2 in Formalin-fixed, Paraffin-embedded Human Cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase -streptavidin and chromagen.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab118898 尚未被引用在任何文献中。