AB109724

重组Anti-MALT1/MLT抗体[EPR604]

Anti-MALT1/MLT antibody [EPR604]

RabMAb
Recombinant
了解详情

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(1 Publication)

Rabbit Recombinant Monoclonal MALT1/MLT antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

查看别名

MLT, MALT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT lymphoma-associated translocation, Paracaspase

1 Images

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Western blot - Anti-MALT1/MLT antibody [EPR604] (AB109724)

All lanes:

Western blot - Anti-MALT1/MLT antibody [EPR604] (ab109724) at 1/1000 dilution

Lane 1:

Jurkat lysate at 10 µg

Lane 2:

K562 lysate at 10 µg

Lane 3:

Bone marrow lysate at 10 µg

Lane 4:

PBMC lysates at 10 µg

Secondary

All lanes:

Standard HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 92 kDa

false

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR604

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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产品详情

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Protease that enhances BCL10-induced activation : acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (PubMed : 11262391, PubMed : 18264101, PubMed : 24074955). Mediates BCL10 cleavage : MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion (PubMed : 11262391, PubMed : 18264101). Involved in the induction of T helper 17 cells (Th17) differentiation (PubMed : 11262391, PubMed : 18264101). Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity). Also mediates cleavage of N4BP1 in T-cells following TCR-mediated activation, leading to N4BP1 inactivation (PubMed : 31133753). May also have ubiquitin ligase activity : binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity (PubMed : 14695475).

See full target information MALT1

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 300:105644 PubMed38218226

2024

Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase.

Applications

Unspecified application

Species

Unspecified reactive species

Dönem Avci,Ronny Heidasch,Martina Costa,Christian Lüchtenborg,Dipali Kale,Britta Brügger,Marius K Lemberg

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

重组Anti-MALT1/MLT抗体[EPR604]

Anti-MALT1/MLT antibody [EPR604]

Western blot - Anti-MALT1/MLT antibody [EPR604] (AB109724)

关键信息

宿主种属

克隆

克隆号

亚型

不含载体蛋白

反应种属

应用

免疫原