Anti-MAGED1/NRAGE抗体(ab104627)
Key features and details
- Rabbit polyclonal to MAGED1/NRAGE
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-MAGED1/NRAGE抗体 -
描述
兔多克隆抗体to MAGED1/NRAGE -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat
预测可用于: Human
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免疫原
Synthetic peptide corresponding to Mouse MAGED1/NRAGE aa 650-750 conjugated to keyhole limpet haemocyanin (Cysteine residue).
Database link: Q9QYH6 -
阳性对照
- PC12 cell extracts
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab104627于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 86 kDa.
|
| 说明 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 86 kDa. |
靶标
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功能
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed. -
组织特异性
Expressed in bone marrow stromal cells from both multiple myeloma patients and healthy donors. Seems to be ubiquitously expressed. -
序列相似性
Contains 1 MAGE domain. -
细胞定位
Cytoplasm. Cell membrane. Nucleus. Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF. - Information by UniProt
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数据库链接
- Entrez Gene: 9500 Human
- Entrez Gene: 84469 Rat
- Omim: 300224 Human
- SwissProt: Q9Y5V3 Human
- SwissProt: Q9ES73 Rat
- Unigene: 5258 Human
- Unigene: 54596 Rat
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别名
- DLXIN 1 antibody
- MAGD1_HUMAN antibody
- MAGE D1 antigen antibody
see all
图片
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Western blot - Anti-MAGED1/NRAGE antibody (ab104627)All lanes : Anti-MAGED1/NRAGE antibody (ab104627) at 1/500 dilution
Lane 1 : PC12 cell extracts with MAGED1 blocking peptide
Lane 2 : PC12 cell extracts
Predicted band size: 86 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab104627 尚未被引用在任何文献中。