Anti-MAGEA1抗体[SPM282] (ab25834)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody [SPM282] (ab25834)](https://www.abcam.cn/ps/products/25/ab25834/Images/ab25834-294970-anti-mage-1-antibody-spm282-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody [SPM282] (ab25834)")
Key features and details
- Mouse monoclonal [SPM282] to MAGEA1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-MAGEA1抗体[SPM282]
参阅全部 MAGEA1 一抗 -
描述
小鼠单克隆抗体[SPM282] to MAGEA1 -
宿主
Mouse -
特异性
ab25834 recognises MAGE-1.
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经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Rat, Dog
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免疫原
Recombinant full length protein corresponding to Human MAGEA1.
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阳性对照
- Colo32 cells Germ cells in testis.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.0268% PBS, BSA -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
SPM282 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25834于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/25. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
IHC-P
1/25. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
靶标
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功能
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. -
组织特异性
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas. -
序列相似性
Contains 1 MAGE domain. -
细胞定位
Cytoplasm. Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 4100 Human
- Omim: 300016 Human
- SwissProt: P43355 Human
- Unigene: 72879 Human
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别名
- Antigen MZ2 E antibody
- Antigen MZ2-E antibody
- Cancer/testis antigen 1.1 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody [SPM282] (ab25834)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling MAGEA1 with ab25834.
数据表及文件
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Datasheet download
文献 (0)
ab25834 尚未被引用在任何文献中。
