Anti-MACC1抗体(ab223710)
Key features and details
- Rabbit polyclonal to MACC1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MACC1抗体
参阅全部 MACC1 一抗 -
描述
兔多克隆抗体to MACC1 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Orangutan
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免疫原
Recombinant fragment corresponding to Human MACC1 aa 1-100.
Database link: Q6ZN28 -
阳性对照
- IHC-P: Human kidney, colon, colorectal cancer and stomach cancer tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab223710于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. -
组织特异性
Preferentially expressed in metastasizing tumors. -
序列相似性
Contains 1 SH3 domain. -
细胞定位
Cytoplasm. Nucleus. Mainly found in the cytoplasm in non-metastasizing tumors. - Information by UniProt
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数据库链接
- Entrez Gene: 346389 Human
- Entrez Gene: 612646 Human
- SwissProt: Q6ZN28 Human
- SwissProt: Q5RBY8 Orangutan
- Unigene: 598388 Human
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别名
- 7A5 antibody
- MACC1 antibody
- MACC1_HUMAN antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MACC1 antibody (ab223710)
Paraffin embedded sections of human colorectal cancer were stained for MACC1 with ab223710 at 1/50 dilution in immunohistochemical analysis.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MACC1 antibody (ab223710)Paraffin embedded sections of human stomach cancer were stained for MACC1 with ab223710 at 1/50 dilution in immunohistochemical analysis.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MACC1 antibody (ab223710)Paraffin embedded sections of human colon were stained for MACC1 with ab223710 at 1/50 dilution in immunohistochemical analysis.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MACC1 antibody (ab223710)Paraffin embedded sections of human kidney were stained for MACC1 with ab223710 at 1/50 dilution in immunohistochemical analysis.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab223710 尚未被引用在任何文献中。