Anti-LYST抗体[3H1] (ab118121)
![Sandwich ELISA - Anti-LYST antibody [3H1] (ab118121)](https://www.abcam.cn/ps/products/118/ab118121/Images/LYST-Primary-antibodies-ab118121-1.jpg "Sandwich ELISA - Anti-LYST antibody [3H1] (ab118121)")
Key features and details
- Mouse monoclonal [3H1] to LYST
- Suitable for: Sandwich ELISA
- Reacts with: Human
- Isotype: IgG2b
概述
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产品名称
Anti-LYST抗体[3H1]
参阅全部 LYST 一抗 -
描述
小鼠单克隆抗体[3H1] to LYST -
宿主
Mouse -
经测试应用
适用于: Sandwich ELISAmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment, corresponding to amino acids 1-101 of Human LYST with proprietary tag (NP_000072).
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常规说明
This product was changed from ascites to tissue culture supernatant on 15 May 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4
Constituent: 99% PBS -
Concentration information loading... -
纯度
Tissue culture supernatant -
纯化说明
Purified from TCS. -
克隆
单克隆 -
克隆编号
3H1 -
同种型
IgG2b -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab118121于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Sandwich ELISA |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
Sandwich ELISA
Use at an assay dependent concentration. |
靶标
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功能
May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. -
组织特异性
Abundantly expressed in adult and fetal thymus, peripheral blood leukocytes, bone marrow and several regions of the adult brain. -
疾病相关
Defects in LYST are the cause of Chediak-Higashi syndrome (CHS) [MIM:214500]. CHS is a rare autosomal recessive disorder characterized by hypopigmentation, severe immunologic deficiency, a bleeding tendency, neurologic abnormalities, abnormal intracellular transport to and from the lysosome, and giant inclusion bodies in a variety of cell types. Most patients die at an early age unless they receive an allogeneic hematopoietic stem cell transplant (SCT). -
序列相似性
Contains 1 BEACH domain.
Contains 7 WD repeats. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 1130 Human
- Omim: 606897 Human
- SwissProt: Q99698 Human
- Unigene: 532411 Human
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别名
- Beige homolog antibody
- beige protein antibody
- Chediak-Higashi syndrome 1 antibody
see all
图片
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Sandwich ELISA - Anti-LYST antibody [3H1] (ab118121)
Detection limit for recombinant tagged LYST is 0.03 ng/ml as a capture antibody.
This image was generated using the ascites version of the product.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab118121 尚未被引用在任何文献中。
