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AB244607

重组Anti-Lymphotactin/ATAC抗体[EPR20426-92] - BSA and Azide free (Capture)

Anti-Lymphotactin/ATAC antibody [EPR20426-92] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal XCL1 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

查看别名

LTN, SCYC1, XCL1, Lymphotactin, ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1

1 Images
Sandwich ELISA - Anti-Lymphotactin/ATAC antibody [EPR20426-92] - BSA and Azide free (Capture) (AB244607)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Lymphotactin/ATAC antibody [EPR20426-92] - BSA and Azide free (Capture) (AB244607)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab264620).

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR20426-92

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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产品详情

ab244607 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human XCL1. The recommended pair for sandwich ELISA is:
Capture: ab244607, Human XCL1 Capture Antibody (unconjugated)
Detector: ab244857, Human XCL1 Detector Antibody (unconjugated)
The reference range value is 97.48 - 2800 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Lymphotactin also known as ATAC (Activation-induced T cell-derived and chemokine related cytokine) is a chemokine that plays an important role in immune system communication. It has a molecular mass of around 12 kDa. Lymphotactin is unique because it is the only member of the C class chemokines lacking one of the conserved cysteines found in other chemokines. It is primarily expressed in activated T cells and NK cells and can be found in tissues such as the spleen thymus and lymph nodes.
Biological function summary

This chemokine specifically attracts T cells and NK cells to sites of inflammation. It is not known to form part of larger molecular complexes. Lymphotactin contributes to cell signaling events that direct immune cells to infection sites or areas of tissue damage ensuring specific and effective immune responses. This targeting is especially useful during the immune system’s response to pathogens aiding in the clearance of infections.

Pathways

Lymphotactin influences immune response pathways especially those involved in cell-mediated responses. It interacts with the chemokine receptor XCR1 which plays a role in immune surveillance by guiding T cells to infected zones. Lymphotactin's activity bridges innate and adaptive immunity by directing cells where they are needed most linking it to pathways like cytokine signaling and inflammatory response.

Lymphotactin has a role in conditions such as inflammatory bowel disease and certain autoimmune disorders. Overproduction or dysregulation can exacerbate these conditions by leading to excessive immune cell infiltration and inflammation. The chemokine connects to proteins like XCR1 in these disease contexts influencing cellular migration and the extent of an inflammatory response. Understanding its disease-related interactions helps in the development of targeted therapies.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
See full target information XCL1
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搭配使用产品

Assay Kits

AB264620

Human XCL1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human XCL1 ELISA Kit (AB264620)

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Sandwich ELISA - Anti-LKB1 antibody [EPR19490-176] - BSA and Azide free (Detector) (AB244998)

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Primary Antibodies

AB91279

Anti-liver Arginase antibody

Immunoprecipitation - Anti-liver Arginase antibody (AB91279)

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Primary Antibodies

AB302522

Anti-XCL1+XCL2 antibody [EPR26181-30]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry - Anti-XCL1+XCL2 antibody [EPR26181-30] (AB302522)

  • 0
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Assay Kits

AB264620

Human XCL1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human XCL1 ELISA Kit (AB264620)

  • 0
  • 0

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