Anti-LRIG2抗体(ab121472)
Key features and details
- Rabbit polyclonal to LRIG2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-LRIG2抗体
参阅全部 LRIG2 一抗 -
描述
兔多克隆抗体to LRIG2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence, corresponding to C terminal amino acids 852-1050 of Human LRIG2.
-
阳性对照
- ICC/IF: human cell line A-431 IHC: Human epididymis and skeletal muscle tissue
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121472于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
|
| ICC/IF |
Use a concentration of 0.2 - 0.25 µg/ml.
|
| 说明 |
|---|
|
IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
|
ICC/IF
Use a concentration of 0.2 - 0.25 µg/ml. |
靶标
-
组织特异性
Detected in all tissues analyzed. -
序列相似性
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
细胞定位
Cell membrane. Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 9860 Human
- Omim: 608869 Human
- SwissProt: O94898 Human
- Unigene: 448972 Human
-
别名
- KIAA0806 antibody
- Leucine rich repeats and immunoglobulin like domains 2 antibody
- Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody
see all
图片
-
Immunocytochemistry/ Immunofluorescence - Anti-LRIG2 antibody (ab121472)
ab121472 at 2 µg/ml staining LRIG2 in human cell line A-43 tissue by Immunocytochemistry/Immunofluorescence
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRIG2 antibody (ab121472)ab121472 at 1/10 dilution staining LRIG2 in Human epididymis tissue by Immunohistochemistry.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRIG2 antibody (ab121472)ab121472 at 1/10 dilution staining LRIG2 in Human skeletal muscle tissue by Immunohistochemistry.
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab121472 被引用在 2 文献中.
- Hu J et al. LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization. J Immunother Cancer 10:N/A (2022). PubMed: 36096529
- Suh DS et al. LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle. Oncogenesis 7:3 (2018). PubMed: 29358688