Anti-LRBA/BGL抗体(ab121765)
Key features and details
- Rabbit polyclonal to LRBA/BGL
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-LRBA/BGL抗体
参阅全部 LRBA/BGL 一抗 -
描述
兔多克隆抗体to LRBA/BGL -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human LRBA/BGL aa 907-1038.
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阳性对照
- Human rectum tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121765于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. -
组织特异性
Ubiquitous. -
序列相似性
Contains 1 BEACH domain.
Contains 6 WD repeats. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cell membrane. Endoplasmic reticulum. Golgi apparatus > trans-Golgi network. Lysosome. - Information by UniProt
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数据库链接
- Entrez Gene: 987 Human
- Omim: 606453 Human
- SwissProt: P50851 Human
- Unigene: 480938 Human
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别名
- Beige-like protein antibody
- BGL antibody
- C80285 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRBA/BGL antibody (ab121765)
ab121765 at 1/200 dilution staining LRBA/BGL in paraffin embedded Human rectum tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab121765 被引用在 1 文献中.
- Alangari A et al. LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol 130:481-8.e2 (2012). PubMed: 22721650