Anti-LPA-3抗体(ab23692)
Key features and details
- Rabbit polyclonal to LPA-3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-LPA-3抗体
参阅全部 LPA-3 一抗 -
描述
兔多克隆抗体to LPA-3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rat
-
免疫原
Synthetic peptide corresponding to Mouse LPA-3 aa 1-100 (N terminal).
Database link: Q9EQ31 -
阳性对照
- WB: HepG2 cell lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 50% Glycerol, 0.1% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab23692于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/200. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
|
| 说明 |
|---|
|
WB
1/200. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
靶标
-
功能
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins. -
组织特异性
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 23566 Human
- Entrez Gene: 66025 Rat
- Omim: 605106 Human
- SwissProt: Q9UBY5 Human
- SwissProt: Q8K5E0 Rat
- Unigene: 674915 Human
- Unigene: 64507 Rat
-
别名
- Calcium mobilizing lysophosphatidic acid receptor LP A3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA 3 antibody
- Calcium mobilizing lysophosphatidic acid receptor LPA3 antibody
see all
图片
-
Western blot - Anti-LPA-3 antibody (ab23692)Anti-LPA-3 antibody (ab23692) at 2.5 µg/ml + HepG2 cell lysate (30 µg).
Predicted band size: 40 kDa
Observed band size: 40 kDa
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (11)
ab23692 被引用在 11 文献中.
- Choi SH et al. Visualization of the binding between gintonin, a Panax ginseng-derived LPA receptor ligand, and the LPA receptor subtypes and transactivation of the EGF receptor. J Ginseng Res 46:348-356 (2022). PubMed: 35600777
- Chiang JC et al. Lysophosphatidic acid receptors 2 and 3 regulate erythropoiesis at different hematopoietic stages. Biochim Biophys Acta Mol Cell Biol Lipids 1866:158818 (2021). PubMed: 33035680
- Lee R et al. Effect of the Gintonin-Enriched Fraction on Glucagon-Like-Protein-1 Release. Molecules 26:N/A (2021). PubMed: 34684879
- Wei M et al. Downregulated circular RNA zRANB1 mediates Wnt5a/ß-Catenin signaling to promote neuropathic pain via miR-24-3p/LPAR3 axis in CCI rat models. Gene 761:145038 (2020). PubMed: 32777532
- Li GC et al. Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting LPAR3. J Cell Physiol 234:22331-22342 (2019). PubMed: 31140597