Anti-LNK抗体(ab128222)
Key features and details
- Rabbit polyclonal to LNK
- Suitable for: ELISA, IHC-Fr, IHC-P, WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-LNK抗体
参阅全部 LNK 一抗 -
描述
兔多克隆抗体to LNK -
宿主
Rabbit -
经测试应用
适用于: ELISA, IHC-Fr, IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Monkey
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免疫原
Synthetic peptide derived from the C terminal domain of Human LNK.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
存储溶液
Constituents: 1.21% Tris, 0.75% Glycine, 2% Sucrose -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab128222于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
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| IHC-Fr |
Use at an assay dependent concentration.
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| IHC-P |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
ELISA
Use at an assay dependent concentration. |
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IHC-Fr
Use at an assay dependent concentration. |
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IHC-P
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
靶标
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功能
Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. -
组织特异性
Preferentially expressed by lymphoid cell lines. -
疾病相关
Genetic variations in SH2B3 are associated with susceptibility to celiac disease type 13 (CELIAC13)[MIM:612011]; also known as susceptibility to gluten-sensitive enteropathy type 13. Celiac disease is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins. In its classic form, celiac disease is characterized in children by malabsorption and failure to thrive.
Genetic variations in SH2B3 are associated with susceptibility to insulin-dependent diabetes mellitus (IDDM) [MIM:222100]; also known as diabetes mellitus type 1. IDDM normally starts in childhood or adolescence and is caused by the body's own immune system which destroys the insulin-producing beta cells in the pancreas. Classical features are polydipsia, polyphagia and polyuria, due to hyperglycemia-induced osmotic diuresis. -
序列相似性
Belongs to the SH2B adapter family.
Contains 1 PH domain.
Contains 1 SH2 domain. -
翻译后修饰
Tyrosine phosphorylated by LCK. - Information by UniProt
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数据库链接
- Entrez Gene: 10019 Human
- Entrez Gene: 16923 Mouse
- Entrez Gene: 58838 Rat
- Omim: 605093 Human
- SwissProt: Q9UQQ2 Human
- SwissProt: O09039 Mouse
- SwissProt: P50745 Rat
- Unigene: 506784 Human
see all -
别名
- IDDM20 antibody
- Lymphocyte adapter protein antibody
- Lymphocyte specific adapter protein antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab128222 尚未被引用在任何文献中。