Anti-LITAF抗体
Anti-LITAF antibody
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(2 Publications)
Rabbit Polyclonal LITAF antibody. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human LITAF.
查看别名
PIG7, SIMPLE, LITAF, Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, p53-induced gene 7 protein
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LITAF antibody (AB187533)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human endometrial cancer tissue labelling Tbx1 with ab187533 at 1/200. Magnification : 400x.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LITAF antibody (AB187533)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human thyroid cancer tissue labelling Tbx1 with ab187533 at 1/200. Magnification : 400x.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LITAF antibody (AB187533)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling Tbx1 with ab187533 at 1/200. Magnification : 400x.
- WB
Supplier Data
Western blot - Anti-LITAF antibody (AB187533)
All lanes:
Western blot - Anti-LITAF antibody (ab187533) at 1/500 dilution
Lane 1:
K562 cell line extract
Lane 2:
HeLa cell line extract
Lane 3:
HepG2 cell line extract
Lane 4:
BT474 cell line extract
Predicted band size: 17 kDa
false
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The function of LITAF extends to the regulation of inflammation. This protein acts by modulating the transcription of pro-inflammatory cytokines including TNF-alpha. As part of complexes LITAF may work in collaboration with other molecules to regulate these inflammatory responses. This regulation is vital for maintaining balance within immune responses playing a significant part in defending against hostile pathogens while avoiding excessive tissue damage caused by inflammation.
Pathways
The immune and inflammatory responses prominently feature the LITAF protein. It plays a role in the TNF signaling pathway where it helps regulate the expression of tumor necrosis factor and other inflammatory mediators. LITAF is closely related to molecules like TRAF and NF-kB within these pathways facilitating various immune functions and responses. These interactions are essential for correct signaling and action during immune challenges.
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靶点信息
文献 (2)
Recent publications for all applications. Explore the full list and refine your search
Environmental toxicology 36:1618-1627 PubMed33908139
2021
Applications
Unspecified application
Species
Unspecified reactive species
Cellular signalling 55:40-52 PubMed30552989
2018
Applications
Unspecified application
Species
Unspecified reactive species
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