AB176347

重组Anti-Lipin 2/LPIN2抗体[EPR12479]

Anti-Lipin 2/LPIN2 antibody [EPR12479]

RabMAb
Recombinant
了解详情

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(6 Publications)

Rabbit Recombinant Monoclonal Lipin 2/LPIN2 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 6 publications.

查看别名

KIAA0249, LPIN2, Phosphatidate phosphatase LPIN2, Lipin-2

2 Images

Flow Cytometry (Intracellular) - Anti-Lipin 2/LPIN2 antibody [EPR12479] (AB176347)

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-Lipin 2/LPIN2 antibody [EPR12479] (AB176347)

Intracellular flow cytometric analysis of permeabilized Jurkat cells labeling Lipin 2/LPIN2 with ab176347 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

Supplier Data

Western blot - Anti-Lipin 2/LPIN2 antibody [EPR12479] (AB176347)

All lanes:

Western blot - Anti-Lipin 2/LPIN2 antibody [EPR12479] (ab176347) at 1/1000 dilution

Lane 1:

Jurkat cell lysate at 10 µg

Lane 2:

HepG2 cell lysate at 10 µg

Lane 3:

293T cell lysate at 10 µg

Lane 4:

HeLa cell lysate at 10 µg

Predicted band size: 99 kDa

false

不同偶联物与剂型 (1)

Carrier free

Anti-Lipin 2/LPIN2 antibody [EPR12479] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR12479

亚型

IgG

不含载体蛋白

反应种属

Human

应用

WB, Flow Cyt (Intra)

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/10 - 1/100", "FlowCytIntra-species-notes": "<a href='/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody." }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }

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产品详情

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式

Liquid

纯度

Tissue culture supernatant

存储溶液

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the endoplasmic reticulum membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Also acts as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.

See full target information LPIN2

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文献 (6)

Recent publications for all applications. Explore the full list and refine your search

eLife 12: PubMed37535403

2023

Promoting axon regeneration by inhibiting RNA N6-methyladenosine demethylase ALKBH5.

Applications

Unspecified application

Species

Unspecified reactive species

Dong Wang,Tiemei Zheng,Songlin Zhou,Mingwen Liu,Yaobo Liu,Xiaosong Gu,Susu Mao,Bin Yu

International immunopharmacology 118:109930 PubMed37001383

2023

Lipin2 ameliorates diabetic encephalopathy via suppressing JNK/ERK-mediated NLRP3 inflammasome overactivation.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaochen Zhang,Shan Huang,Ziyun Zhuang,Xiaolin Han,Min Xie,Shuyan Yu,Mengyu Hua,Zhonghao Liang,Chao Meng,Ling Yin,Xianghua Zhuang,Shihong Chen

Biomolecules & therapeutics 30:246-256 PubMed34815367

2021

Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Jia-Yi Dou,Yu-Chen Jiang,Zhong-He Hu,Kun-Chen Yao,Ming-Hui Yuan,Xiao-Xue Bao,Mei-Jie Zhou,Yue Liu,Zhao-Xu Li,Li-Hua Lian,Ji-Xing Nan,Yan-Ling Wu

Frontiers in pharmacology 12:738689 PubMed34690775

2021

L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Zhen-Yu Cui,Xin Han,Yu-Chen Jiang,Jia-Yi Dou,Kun-Chen Yao,Zhong-He Hu,Ming-Hui Yuan,Xiao-Xue Bao,Mei-Jie Zhou,Yue Liu,Li-Hua Lian,Xian Zhang,Ji-Xing Nan,Yan-Ling Wu

IUBMB life 72:533-543 PubMed31967386

2020

Phosphatidic acid metabolism regulates neuroendocrine secretion but is not under the direct control of lipins.

Applications

Unspecified application

Species

Unspecified reactive species

Claire Baneux,Emeline Tanguy,Tamou Thahouly,Alessio Vitale,Sylvette Chasserot-Golaz,Marie-France Bader,Stéphane Gasman,Nicolas Vitale

Cell reports 26:884-892.e4 PubMed30673611

2019

Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Yongxu Zhao,Zhuanghui Feng,Yongxian Zhang,Yingmin Sun,Yanhao Chen,Xiaojian Liu,Shuang Li,Tingting Zhou,Lanlan Chen,Yuda Wei,Danjun Ma,Kathy O Lui,Hao Ying,Yan Chen,Qiurong Ding

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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重组Anti-Lipin 2/LPIN2抗体[EPR12479]