Anti-LIM1/LHX1抗体

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

LIM1 serves as a regulator of gene expression critical for proper tissue and organ formation. During early embryogenesis it coordinates the development of structures in the central nervous system and urogenital systems. LIM1 often functions within a transcriptional complex involving other proteins facilitating the activation or repression of target gene transcription. This action is important for the precise spatial and temporal patterning required for organ and tissue differentiation.

Pathways

LIM1 integrates into several signaling pathways that coordinate developmental cues. Two significant pathways include the Wnt and BMP pathways. Within these LIM1 interacts with other key proteins like β-catenin and Smad proteins ensuring proper transmission of developmental signals. These pathways underpin the processes of pattern formation and axis specification positioning LIM1 as a central regulatory node within these systems.