Anti-Lass5抗体(ab73289)
Key features and details
- Rabbit polyclonal to Lass5
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-Lass5抗体
参阅全部 Lass5 一抗 -
描述
兔多克隆抗体to Lass5 -
宿主
Rabbit -
特异性
ab73289 may cross-react with the highly homologous Lass6. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
An 18 amino acid peptide near the amino terminus of human Lass5
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阳性对照
- WB: Rat brain tissue lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73289于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa). |
靶标
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功能
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner. -
序列相似性
Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain. -
细胞定位
Nucleus membrane. Endoplasmic reticulum membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 366984 Rat
- SwissProt: B2RYI9 Rat
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别名
- CerS5 antibody
- FLJ25304 antibody
- LAG1 homolog ceramide synthase 5 antibody
see all
图片
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Western blot - Anti-Lass5 antibody (ab73289)Lane 1 : Anti-Lass5 antibody (ab73289) at 1 µg/ml
Lane 2 : Anti-Lass5 antibody (ab73289) at 2 µg/ml
All lanes : Rat brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 46 kDa
Observed band size: 46 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab73289 被引用在 3 文献中.
- Pani T et al. Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype. Cell Death Dis 12:171 (2021). PubMed: 33568634
- Markowski AR et al. Ceramides Profile Identifies Patients with More Advanced Stages of Colorectal Cancer. Biomolecules 10:N/A (2020). PubMed: 32325909
- Ji R et al. Increased de novo ceramide synthesis and accumulation in failing myocardium. JCI Insight 2:N/A (2017). WB ; Human . PubMed: 28469091