JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB20098

Anti-Lambda Light chain抗体

Anti-Lambda Light chain antibody

Be the first to review this product! Submit a review

|

(0 Publication)

Goat Polyclonal LV151 antibody. Suitable for ELISA and reacts with Human samples. Immunogen corresponding to Native Full Length Protein corresponding to Human IGLV1-51.

查看别名

Immunoglobulin lambda variable 1-51, Ig lambda chain V-I region BL2, Ig lambda chain V-I region EPS, Ig lambda chain V-I region NEW, Ig lambda chain V-I region NIG-64, IGLV1-51

关键信息

宿主种属

Goat

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

ELISA

applications

免疫原

Native Full Length Protein corresponding to Human IGLV1-51.

P01701

特异性

Monospecific by immunoelectrophoresis when tested against pooled human plasma and twice concentrated pooled human serum.

style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>" } } }
style
left-column

您是否考虑以下替代产品？

AB124719

Anti-Lambda Light chain antibody [EPR5367-62]

0
0 Reviews
查看产品
为什么推荐这个？

为向您提供最高品质的产品，我们在不断升级产品范围。我们选择了这个替代产品供您参考，因为它提供了更好的性能，更容易和更方便的使用，或交期更快。

style
left-column
style
left-column

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein G
纯化说明
Delipidation and ion exchange chromatography. Product is 0.2um filtered.
存储溶液
Preservative: 0.1% Sodium azide Constituents: Tris buffered saline
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
储存信息
Avoid freeze / thaw cycle
style
left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Lambda Light Chain also known as lambda chain or lambda protein forms a part of immunoglobulins (antibodies). Its mass typically ranges between 22 to 24 kDa. This protein is expressed primarily in B cells. Specifically it pairs with heavy chains to form the complete antibody molecule. It participates in the antigen recognition process supporting the immune system's defense mechanisms.
Biological function summary

Lambda Light Chain participates in immunological functions by contributing to the antigen-binding site of antibodies. It exists as a part of the immunoglobulin complex. The lambda chain alongside heavy chains forms the variable part of antibodies allowing specificity in antigen recognition. Its variation leads to a diverse antibody repertoire which is important for recognizing a wide range of pathogens.

Pathways

Lambda Light Chain fits into pathways involving adaptive immune responses. It is important in antigen processing and presentation pathways. In this context it interacts with the heavy chains which together drive the specificity and efficiency of immune response pathways. It also associates with proteins like the major histocompatibility complex (MHC) which facilitates antigen presentation to T cells.

Lambda Light Chain associates with multiple myeloma a cancer of plasma cells and light chain amyloidosis a disorder where light chains accumulate as amyloid fibrils in tissues. In these conditions proteins like immunoglobulin heavy chain and albumin often interact with or are affected by lambda chains providing insights into disease mechanisms and potential targets for therapeutic intervention.
style
left-column
style
left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

靶点信息

V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed : 24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268).
See full target information IGLV1-51
style
left-column
style
left-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。
style
left-column
style
right-column

关联产品

Select an associated product type
Alternative Product
Primary Antibodies

AB187370

Anti-Lambda Light chain antibody [LcN-2]

primary-antibodies

lambda-light-chain-antibody-lcn-2-ab187370

0

(0 reviews)

Alternative Product
Primary Antibodies

AB227653

Anti-Lambda Light chain antibody [SP147]

primary-antibodies

lambda-light-chain-antibody-sp147-ab227653

0

(0 reviews)

Alternative Product
Primary Antibodies

AB200966

HRP Anti-Lambda Light chain antibody [EPR5367-62]

primary-antibodies

hrp-lambda-light-chain-antibody-epr5367-62-ab200966

0

(0 reviews)

Alternative Product
Primary Antibodies

AB245750

Anti-Lambda Light chain antibody [SP147] - BSA and Azide free

primary-antibodies

lambda-light-chain-antibody-sp147-bsa-and-azide-free-ab245750

0

(0 reviews)

Alternative Product
Primary Antibodies

AB185131

Anti-Lambda Light chain antibody [EPR5367-62] - BSA and Azide free

primary-antibodies

lambda-light-chain-antibody-epr5367-62-bsa-and-azide-free-ab185131

0

(0 reviews)

style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com