Key features and details
- Mouse monoclonal [3B10-5B10] to KRT81
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG2b
参阅全部 KRT81 一抗
描述小鼠单克隆抗体[3B10-5B10] to KRT81
经测试应用适用于: WB, ICC/IF, IHC-Pmore details
This product was changed from ascites to tissue culture supernatant on 27/June/2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration information loading...
纯度Tissue culture supernatant
纯化说明Purified from TCS.
The Abpromise guarantee
IF/ICC: Use at a concentration of 10 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
组织特异性Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
疾病相关Defects in KRT81 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
序列相似性Belongs to the intermediate filament family.
- Information by UniProt
- 1 antibody
- basic antibody
- ghHb 1 antibody
KRT81 antibody (ab55407) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human esophagus. This was producted using the ascites version of the product.
KRT81 antibody (ab55407) used in immunofluorescence at 10ug/ml on HeLa cells. This was producted using the ascites version of the product.
KRT81 antibody (ab55407) at 1ug/lane + HepG2 cell lysate at 25ug/lane. This was producted using the ascites version of the product.
ab55407 被引用在 2 文献中.
- Wang X et al. Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells. Mol Cancer 21:133 (2022). PubMed: 35733218
- Zhang X et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics 11:5650-5674 (2021). PubMed: 33897873