Anti-KIF5A + KIF5B + KIF5C抗体(ab62105)
Key features and details
- Rabbit polyclonal to KIF5A + KIF5B + KIF5C
- Suitable for: ICC, WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-KIF5A + KIF5B + KIF5C抗体
参阅全部 KIF5A + KIF5B + KIF5C 一抗 -
描述
兔多克隆抗体to KIF5A + KIF5B + KIF5C -
宿主
Rabbit -
经测试应用
适用于: ICC, WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human KIF5A + KIF5B + KIF5C.
Database link: Q12840 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab62105于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC |
Use a concentration of 5 µg/ml.
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| WB |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 120 kDa (predicted molecular weight: 110 kDa).
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| 说明 |
|---|
|
ICC
Use a concentration of 5 µg/ml. |
|
WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 120 kDa (predicted molecular weight: 110 kDa). |
靶标
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相关性
The kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; this antibody recognizes all three. Mutations in one of the isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias. -
细胞定位
Uniformly distributed between soma and neurites in hippocampal neurons -
数据库链接
- Entrez Gene: 3798 Human
- Entrez Gene: 3799 Human
- Entrez Gene: 3800 Human
- SwissProt: O60282 Human
- SwissProt: P33176 Human
- SwissProt: Q12840 Human
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别名
- KIF5A antibody
- KIF5B antibody
- KIF5C antibody
see all
图片
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Western blot - Anti-KIF5A + KIF5B + KIF5C antibody (ab62105)Lane 1 : Anti-KIF5A + KIF5B + KIF5C antibody (ab62105) at 0.5 µg/ml
Lane 2 : Anti-KIF5A + KIF5B + KIF5C antibody (ab62105) at 1 µg/ml
All lanes : K562 cell lysate
Predicted band size: 110 kDa
Observed band size: 120 kDa why is the actual band size different from the predicted? -
Immunocytochemistry - Anti-KIF5A + KIF5B + KIF5C antibody (ab62105)ab62105 at 5µg/ml staining KIF5A + KIF5B + KIF5C in human K562 cells by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab62105 被引用在 1 文献中.
- Zollo M et al. PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment. Brain 140:940-952 (2017). WB . PubMed: 28334956