AB72417

Anti-KIF18A抗体

Name: KIF18A抗体 (ab72417)| Abcam中文官网
Brand: Abcam Limited
SKU: AB72417
Price: 4606 CNY
Availability: InStock

Anti-KIF18A antibody

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(8 Publications)

Rabbit Polyclonal KIF18A antibody. Suitable for IP, WB and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human KIF18A.

查看别名

OK/SW-cl.108, KIF18A, Kinesin-like protein KIF18A, Marrow stromal KIF18A, MS-KIF18A

2 Images

Unknown

Immunoprecipitation - Anti-KIF18A antibody (AB72417)

Detection of KIF18A by Western Blot of Immunprecipitate.
ab72417 at 1µg/ml staining KIF18A in HeLa whole cell lysate immunoprecipitated using ab72417 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection : Chemiluminescence with exposure time of 30 seconds.

All lanes:

Immunoprecipitation - Anti-KIF18A antibody (ab72417)

Predicted band size: 102 kDa

false

Unknown

Western blot - Anti-KIF18A antibody (AB72417)

All lanes:

Western blot - Anti-KIF18A antibody (ab72417) at 0.04 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

HeLa whole cell lysate at 5 µg

Lane 4:

293T whole cell lysate at 50 µg

Predicted band size: 102 kDa

Observed band size: 117 kDa

true

Exposure time: 3min

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

WB, IP

applications

免疫原

Synthetic Peptide within Human KIF18A. The exact immunogen used to generate this antibody is proprietary information.

Q8NI77

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-5 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

ab72417 was affinity purified using an epitope specific to KIF18A immobilized on solid support.

存储溶液

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.

See full target information KIF18A

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文献 (8)

Recent publications for all applications. Explore the full list and refine your search

The FEBS journal 292:3910-3925 PubMed39954259

2025

Kinesin-like protein KIF18A is required for faithful coordination of chromosome congression with cytokinesis.

Applications

Unspecified application

Species

Unspecified reactive species

Su Hyun Lee,Mi-Sun Kwon,Taerim Lee,Sungchul Hohng,Hyunsook Lee

Cancer biomarkers : section A of Disease markers 41:165-178 PubMed39331093

2024

KIF18A promotes cervical squamous cell carcinoma progression by activating the PI3K/AKT pathway through upregulation of CENPE.

Applications

Unspecified application

Species

Unspecified reactive species

Fengyi Sun,Tiantian Zhao

Journal of Cancer 15:2260-2275 PubMed38495502

2024

Development and Validation of the novel Cuproptosis- and Immune-related Signature for Predicting Prognosis in Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yongping Zhang,Ping Sui,Cheng Zhong,Jiansheng Liu

Frontiers in oncology 13:1211103 PubMed37965453

2023

Development and validation of a novel anoikis-related gene signature in clear cell renal cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Qihang Wu,Yuxiang Sun,Xiangcheng Qin,Maomao Li,Shuaishuai Huang,Xue Wang,Guobin Weng

Aging 15:9182-9192 PubMed37708299

2023

improves migration and invasion of colorectal cancer (CRC) cells through inhibiting signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Liu,Ming Sun,Bin Zhang,Wenyan Zhao

Experimental and therapeutic medicine 25:154 PubMed36911368

2023

KIF18A interacts with PPP1CA to promote the malignant development of glioblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Yang,Qiaorong Zhang,Ziyuan Yang,Jiaming Shu,Lingling Zhang,Yangyang Yao,Xiaolang Wang,Xianxian Liu

Translational cancer research 8:2252-2263 PubMed35116978

2019

KIF18A promotes head and neck squamous cell carcinoma invasion and migration via activation of Akt signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Guancheng Liu,Gengming Cai,Xiaosong He,Donghai Huang,Gangcai Zhu,Changhan Chen,Xin Zhang

Experimental and therapeutic medicine 12:377-383 PubMed27347065

2016

Elevated expression of KIF18A enhances cell proliferation and predicts poor survival in human clear cell renal carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Q I Chen,Bin Cao,Ning Nan,Y U Wang,X U Zhai,Youfang Li,Tie Chong

View all publications

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Anti-KIF18A抗体

Anti-KIF18A antibody

Immunoprecipitation - Anti-KIF18A antibody (AB72417)

Western blot - Anti-KIF18A antibody (AB72417)