Anti-KCNA3抗体(ab61200)
Key features and details
- Rabbit polyclonal to KCNA3
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-KCNA3抗体
参阅全部 KCNA3 一抗 -
描述
兔多克隆抗体to KCNA3 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Synthetic non-phosphopeptide derived from human KCNA3 around the phosphorylation site of tyrosine 135.
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阳性对照
- Human brain tissue and HuvEc cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab61200 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61200于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
1/100 - 1/500.
|
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| IHC-P |
1/50 - 1/100.
|
| 说明 |
|---|
|
ICC/IF
1/100 - 1/500. |
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IHC-P
1/50 - 1/100. |
靶标
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功能
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. -
序列相似性
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily. -
结构域
The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 3738 Human
- Entrez Gene: 16491 Mouse
- Omim: 176263 Human
- SwissProt: P22001 Human
- SwissProt: P16390 Mouse
- Unigene: 169948 Human
- Unigene: 30640 Mouse
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别名
- HGK 5 antibody
- HGK5 antibody
- HLK 3 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNA3 antibody (ab61200)ab61200 at 1/50 dilution staining KCNA3 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
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Immunocytochemistry/ Immunofluorescence - Anti-KCNA3 antibody (ab61200)ab61200 at 1/100 dilution staining KCNA3 in HuvEc cells by Immunofluorescence, in the absence (left) or presence (right) of the immunising peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab61200 尚未被引用在任何文献中。