Anti-Kallikrein 5抗体(ab7283)
Key features and details
- Rabbit polyclonal to Kallikrein 5
- Isotype: IgG
概述
-
产品名称
Anti-Kallikrein 5抗体
参阅全部 Kallikrein 5 一抗 -
描述
兔多克隆抗体to Kallikrein 5 -
宿主
Rabbit -
免疫原
Synthetic peptide, corresponding to amino acids 280-293 of Human KLK5.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
靶标
-
功能
May be involved in desquamation. -
组织特异性
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. -
序列相似性
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
细胞定位
Secreted. - Information by UniProt
-
别名
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
see all
数据表及文件
-
SDS download
-
Datasheet download
文献 (6)
ab7283 被引用在 6 文献中.
- Somogyi O et al. New Data on the Features of Skin Barrier in Hidradenitis Suppurativa. Biomedicines 11:N/A (2023). PubMed: 36672635
- Kapitány A et al. Regional Differences in the Permeability Barrier of the Skin-Implications in Acantholytic Skin Diseases. Int J Mol Sci 22:N/A (2021). PubMed: 34638769
- Furio L et al. Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. J Exp Med 211:499-513 (2014). PubMed: 24534191
- Bonnart C et al. Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest 120:871-82 (2010). IHC-P ; Human . PubMed: 20179351
- Yanagi T et al. Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice. Am J Pathol 177:106-18 (2010). WB, IHC-P ; Mouse . PubMed: 20489143
- Di WL et al. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161:404-12 (2009). WB ; Human . PubMed: 19438860